Usefulness of virtual scale endoscope for early gastrointestinal lesions

Abstract Objectives For early gastrointestinal lesions, size is an important factor in the selection of treatment. Virtual scale endoscope (VSE) is a newly developed endoscope that can measure size more accurately than visual measurement. This study aimed to investigate whether VSE measurement is ac...

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Main Authors: Nobuhisa Minakata, Hiroaki Ikematsu, Fumiaki Kiyomi, Suma Inoue, Takashi Akutagawa, Takashi Watanabe, Tomonori Yano, Ryo Shimoda
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:DEN Open
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Online Access:https://doi.org/10.1002/deo2.386
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author Nobuhisa Minakata
Hiroaki Ikematsu
Fumiaki Kiyomi
Suma Inoue
Takashi Akutagawa
Takashi Watanabe
Tomonori Yano
Ryo Shimoda
author_facet Nobuhisa Minakata
Hiroaki Ikematsu
Fumiaki Kiyomi
Suma Inoue
Takashi Akutagawa
Takashi Watanabe
Tomonori Yano
Ryo Shimoda
author_sort Nobuhisa Minakata
collection DOAJ
description Abstract Objectives For early gastrointestinal lesions, size is an important factor in the selection of treatment. Virtual scale endoscope (VSE) is a newly developed endoscope that can measure size more accurately than visual measurement. This study aimed to investigate whether VSE measurement is accurate for early gastrointestinal lesions of various sizes and morphologies. Methods This study prospectively enrolled patients with early gastrointestinal lesions ≤20 mm in size visually. Lesion sizes were measured in the gastrointestinal tract visually, on endoscopic resection specimens with VSE, and finally on endoscopic resection specimens using a ruler. The primary endpoint was the normalized difference (ND) of VSE measurement. The secondary endpoints were the ND of visual measurement and the variation between NDs of VSE and visual measurements. ND was calculated as (100 × [measured size − true size] / true size) (%). True size was defined as size measured using a ruler. Results This study included 60 lesions from April 2022 to December 2022, with 20 each in the esophagus, stomach, and colon. The lesion size was 14.0 ± 6.3 mm (mean ± standard deviation). Morphologies were protruded, slightly elevated, and flat or slightly depressed type in 8, 24, and 28 lesions, respectively. The primary endpoint was 0.3 ± 8.8%. In the secondary endpoints, the ND of visual measurement was −1.7 ± 29.3%, and the variability was significantly smaller in the ND of VSE measurement than in that of visual measurement (p < 0.001, F‐test). Conclusions VSE measurement is accurate for early gastrointestinal lesions of various sizes and morphologies.
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spelling doaj-art-d53eabcb6b1747c6b51a3aad5c674bfb2025-08-20T02:18:56ZengWileyDEN Open2692-46092025-04-0151n/an/a10.1002/deo2.386Usefulness of virtual scale endoscope for early gastrointestinal lesionsNobuhisa Minakata0Hiroaki Ikematsu1Fumiaki Kiyomi2Suma Inoue3Takashi Akutagawa4Takashi Watanabe5Tomonori Yano6Ryo Shimoda7Department of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba JapanDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba JapanDepartment of Statistics and Data Center Clinical Research Support Center Kyushu Fukuoka JapanDepartment of Internal Medicine Division of Gastroenterology Saga University Saga JapanDepartment of Endoscopic Diagnostics and Therapeutics Saga University Hospital Saga JapanDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba JapanDepartment of Gastroenterology and Endoscopy National Cancer Center Hospital East Chiba JapanDepartment of Endoscopic Diagnostics and Therapeutics Saga University Hospital Saga JapanAbstract Objectives For early gastrointestinal lesions, size is an important factor in the selection of treatment. Virtual scale endoscope (VSE) is a newly developed endoscope that can measure size more accurately than visual measurement. This study aimed to investigate whether VSE measurement is accurate for early gastrointestinal lesions of various sizes and morphologies. Methods This study prospectively enrolled patients with early gastrointestinal lesions ≤20 mm in size visually. Lesion sizes were measured in the gastrointestinal tract visually, on endoscopic resection specimens with VSE, and finally on endoscopic resection specimens using a ruler. The primary endpoint was the normalized difference (ND) of VSE measurement. The secondary endpoints were the ND of visual measurement and the variation between NDs of VSE and visual measurements. ND was calculated as (100 × [measured size − true size] / true size) (%). True size was defined as size measured using a ruler. Results This study included 60 lesions from April 2022 to December 2022, with 20 each in the esophagus, stomach, and colon. The lesion size was 14.0 ± 6.3 mm (mean ± standard deviation). Morphologies were protruded, slightly elevated, and flat or slightly depressed type in 8, 24, and 28 lesions, respectively. The primary endpoint was 0.3 ± 8.8%. In the secondary endpoints, the ND of visual measurement was −1.7 ± 29.3%, and the variability was significantly smaller in the ND of VSE measurement than in that of visual measurement (p < 0.001, F‐test). Conclusions VSE measurement is accurate for early gastrointestinal lesions of various sizes and morphologies.https://doi.org/10.1002/deo2.386colonoscopyendoscopic submucosal dissectionendoscopyprospective studysize perception
spellingShingle Nobuhisa Minakata
Hiroaki Ikematsu
Fumiaki Kiyomi
Suma Inoue
Takashi Akutagawa
Takashi Watanabe
Tomonori Yano
Ryo Shimoda
Usefulness of virtual scale endoscope for early gastrointestinal lesions
DEN Open
colonoscopy
endoscopic submucosal dissection
endoscopy
prospective study
size perception
title Usefulness of virtual scale endoscope for early gastrointestinal lesions
title_full Usefulness of virtual scale endoscope for early gastrointestinal lesions
title_fullStr Usefulness of virtual scale endoscope for early gastrointestinal lesions
title_full_unstemmed Usefulness of virtual scale endoscope for early gastrointestinal lesions
title_short Usefulness of virtual scale endoscope for early gastrointestinal lesions
title_sort usefulness of virtual scale endoscope for early gastrointestinal lesions
topic colonoscopy
endoscopic submucosal dissection
endoscopy
prospective study
size perception
url https://doi.org/10.1002/deo2.386
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