Direct Healthcare Cost of Fracture-related Infection Treatment

Background:. Fracture-related infections (FRIs) pose significant clinical and economic challenges in trauma surgery. Despite advancements in treatment modalities, the economic burden of managing FRIs remains substantial. However, cost analyses are scarce. Therefore, the aim of this study was to anal...

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Main Authors: Nike Walter, MD, Ines Neubauer, MD, Susanne Baertl, MD, Volker Alt, MD, Markus Rupp, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-09-01
Series:JBJS Open Access
Online Access:http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.24.00133
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author Nike Walter, MD
Ines Neubauer, MD
Susanne Baertl, MD
Volker Alt, MD
Markus Rupp, MD
author_facet Nike Walter, MD
Ines Neubauer, MD
Susanne Baertl, MD
Volker Alt, MD
Markus Rupp, MD
author_sort Nike Walter, MD
collection DOAJ
description Background:. Fracture-related infections (FRIs) pose significant clinical and economic challenges in trauma surgery. Despite advancements in treatment modalities, the economic burden of managing FRIs remains substantial. However, cost analyses are scarce. Therefore, the aim of this study was to analyze the direct healthcare costs associated with FRI treatment compared with initial fracture treatment across various fracture types in a level 1 trauma center in Germany. Methods:. A retrospective analysis of 95 patients treated for fractures and FRIs between 2013 and 2020 was conducted. Patients were categorized based on the fracture location: femur, tibia, ankle, and foot. Data collected included fracture characteristics, and costs related to both initial fracture treatment and FRI management. Costs were analyzed using diagnosis-related group (DRG) reimbursement data. The mean DRG reimbursement for initial fracture treatment and FRI treatment was compared to determine the economic impact of FRIs. Results:. The study revealed significant increases in costs for FRI treatment across all fracture types. For femur fractures, the mean reimbursement for initial treatment was €17,617.66, while FRI treatment costs were €31,731.49, resulting in a difference of €14,113.83 and a 1.8-fold increase in costs. Tibia fractures showed an increase from €10,327.70 to €28,024.38 (difference of €17,696.68, 2.7-fold increase of costs). Ankle fractures had a cost increase from €3,790.38 to €17,940.90 (difference of €14,150.52, 4.7-fold increase of costs), and foot fractures showed an increase from €6,557.95 to €23,272.48 (difference of €16,714.53, 3.5-fold increase of costs). Conclusions:. The costs for FRI treatment are substantially higher than those for initial fracture management across all fracture types studied. These findings emphasize the need for effective preventive measures and efficient management protocols to reduce the incidence and financial impact of FRIs. Level of Evidence:. Level III. See Instructions for Authors for a complete description of levels of evidence.
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spelling doaj-art-d52bc0f8df3a41a79faa3d6db2d376812025-08-26T03:24:54ZengWolters KluwerJBJS Open Access2472-72452025-09-0110310.2106/JBJS.OA.24.00133JBJSOA2400133Direct Healthcare Cost of Fracture-related Infection TreatmentNike Walter, MD0Ines Neubauer, MD1Susanne Baertl, MD2Volker Alt, MD3Markus Rupp, MD41 Department for Trauma Surgery, University Hospital Regensburg, Regensburg1 Department for Trauma Surgery, University Hospital Regensburg, Regensburg1 Department for Trauma Surgery, University Hospital Regensburg, Regensburg1 Department for Trauma Surgery, University Hospital Regensburg, Regensburg1 Department for Trauma Surgery, University Hospital Regensburg, RegensburgBackground:. Fracture-related infections (FRIs) pose significant clinical and economic challenges in trauma surgery. Despite advancements in treatment modalities, the economic burden of managing FRIs remains substantial. However, cost analyses are scarce. Therefore, the aim of this study was to analyze the direct healthcare costs associated with FRI treatment compared with initial fracture treatment across various fracture types in a level 1 trauma center in Germany. Methods:. A retrospective analysis of 95 patients treated for fractures and FRIs between 2013 and 2020 was conducted. Patients were categorized based on the fracture location: femur, tibia, ankle, and foot. Data collected included fracture characteristics, and costs related to both initial fracture treatment and FRI management. Costs were analyzed using diagnosis-related group (DRG) reimbursement data. The mean DRG reimbursement for initial fracture treatment and FRI treatment was compared to determine the economic impact of FRIs. Results:. The study revealed significant increases in costs for FRI treatment across all fracture types. For femur fractures, the mean reimbursement for initial treatment was €17,617.66, while FRI treatment costs were €31,731.49, resulting in a difference of €14,113.83 and a 1.8-fold increase in costs. Tibia fractures showed an increase from €10,327.70 to €28,024.38 (difference of €17,696.68, 2.7-fold increase of costs). Ankle fractures had a cost increase from €3,790.38 to €17,940.90 (difference of €14,150.52, 4.7-fold increase of costs), and foot fractures showed an increase from €6,557.95 to €23,272.48 (difference of €16,714.53, 3.5-fold increase of costs). Conclusions:. The costs for FRI treatment are substantially higher than those for initial fracture management across all fracture types studied. These findings emphasize the need for effective preventive measures and efficient management protocols to reduce the incidence and financial impact of FRIs. Level of Evidence:. Level III. See Instructions for Authors for a complete description of levels of evidence.http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.24.00133
spellingShingle Nike Walter, MD
Ines Neubauer, MD
Susanne Baertl, MD
Volker Alt, MD
Markus Rupp, MD
Direct Healthcare Cost of Fracture-related Infection Treatment
JBJS Open Access
title Direct Healthcare Cost of Fracture-related Infection Treatment
title_full Direct Healthcare Cost of Fracture-related Infection Treatment
title_fullStr Direct Healthcare Cost of Fracture-related Infection Treatment
title_full_unstemmed Direct Healthcare Cost of Fracture-related Infection Treatment
title_short Direct Healthcare Cost of Fracture-related Infection Treatment
title_sort direct healthcare cost of fracture related infection treatment
url http://journals.lww.com/jbjsoa/fulltext/10.2106/JBJS.OA.24.00133
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