Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition
The placenta is a transitory structure indispensable for the proper development of the embryo and fetus during mammalian gestation. Like other members of the nuclear receptor family, the peroxisome proliferator-activated receptors (PPARs) are known to be involved in the physiological and pathologic...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2008/758562 |
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| _version_ | 1832561874804146176 |
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| author | Valerie Borel Denis Gallot Geoffroy Marceau Vincent Sapin Loïc Blanchon |
| author_facet | Valerie Borel Denis Gallot Geoffroy Marceau Vincent Sapin Loïc Blanchon |
| author_sort | Valerie Borel |
| collection | DOAJ |
| description | The placenta is a transitory structure indispensable for the proper development of the embryo and fetus during mammalian gestation. Like other members of the nuclear receptor family, the peroxisome proliferator-activated receptors
(PPARs) are known to be involved in the physiological and pathological events occurring during the placentation.
This placental involvement has been recently reviewed focusing on the early stages of placental development (implantation and invasion, etc.), mouse PPARs knockout phenotypes, and cytotrophoblast physiology. In this
review, we describe the placental involvement of PPARs (e.g., fat transport and metabolism, etc.) during the late stages of
gestation and in the amniotic membranes, highlighting their roles in the inflammation process (e.g., chorioamnionitis), metabolic disorders (e.g., diabetes), and parturition. |
| format | Article |
| id | doaj-art-d52991b00ea946689d353d73753e6799 |
| institution | Kabale University |
| issn | 1687-4757 1687-4765 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | PPAR Research |
| spelling | doaj-art-d52991b00ea946689d353d73753e67992025-02-03T01:24:07ZengWileyPPAR Research1687-47571687-47652008-01-01200810.1155/2008/758562758562Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and ParturitionValerie Borel0Denis Gallot1Geoffroy Marceau2Vincent Sapin3Loïc Blanchon4Université d'Auvergne, JE 2447, ARDEMO, Clermont-Ferrand 63000, FranceUniversité d'Auvergne, JE 2447, ARDEMO, Clermont-Ferrand 63000, FranceUniversité d'Auvergne, JE 2447, ARDEMO, Clermont-Ferrand 63000, FranceUniversité d'Auvergne, JE 2447, ARDEMO, Clermont-Ferrand 63000, FranceUniversité d'Auvergne, JE 2447, ARDEMO, Clermont-Ferrand 63000, FranceThe placenta is a transitory structure indispensable for the proper development of the embryo and fetus during mammalian gestation. Like other members of the nuclear receptor family, the peroxisome proliferator-activated receptors (PPARs) are known to be involved in the physiological and pathological events occurring during the placentation. This placental involvement has been recently reviewed focusing on the early stages of placental development (implantation and invasion, etc.), mouse PPARs knockout phenotypes, and cytotrophoblast physiology. In this review, we describe the placental involvement of PPARs (e.g., fat transport and metabolism, etc.) during the late stages of gestation and in the amniotic membranes, highlighting their roles in the inflammation process (e.g., chorioamnionitis), metabolic disorders (e.g., diabetes), and parturition.http://dx.doi.org/10.1155/2008/758562 |
| spellingShingle | Valerie Borel Denis Gallot Geoffroy Marceau Vincent Sapin Loïc Blanchon Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition PPAR Research |
| title | Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition |
| title_full | Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition |
| title_fullStr | Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition |
| title_full_unstemmed | Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition |
| title_short | Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition |
| title_sort | placental implications of peroxisome proliferator activated receptors in gestation and parturition |
| url | http://dx.doi.org/10.1155/2008/758562 |
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