Tetanus Complicated by Dysautonomia: A Case Report and Review of Management
Tetanus is a life-threatening infectious neurological disorder that is now a rare disease due to the institution of wide-spread vaccination strategies. We present an uncommon case of generalized severe tetanus with consequent respiratory failure requiring mechanical ventilation, which was associated...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2021/8842522 |
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| author | Nishant Sharma Si Li Metlapalli Venkata Sravanthi Dan Kazmierski Yichen Wang Amit Sharma Pragya Dhaubhadel |
| author_facet | Nishant Sharma Si Li Metlapalli Venkata Sravanthi Dan Kazmierski Yichen Wang Amit Sharma Pragya Dhaubhadel |
| author_sort | Nishant Sharma |
| collection | DOAJ |
| description | Tetanus is a life-threatening infectious neurological disorder that is now a rare disease due to the institution of wide-spread vaccination strategies. We present an uncommon case of generalized severe tetanus with consequent respiratory failure requiring mechanical ventilation, which was associated with dysautonomia. A 20-year-old unvaccinated female presented with neck stiffness and diffuse muscle spasms following a laceration sustained 3 weeks prior. She was admitted to the intensive care unit for mechanical ventilation and was treated with immunoglobulin, tetanus toxoid, metronidazole, and high doses of sedatives. She also developed dysautonomia, with alternating bradycardia and tachycardia, as well as fluctuating blood pressure. She was successfully extubated and discharged. We also review the epidemiology, pathophysiology, and management of tetanus and discuss dysautonomia in the setting of tetanus. |
| format | Article |
| id | doaj-art-d51ed979ac204e7ebba5106ea5511dde |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-d51ed979ac204e7ebba5106ea5511dde2025-02-03T06:07:39ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/88425228842522Tetanus Complicated by Dysautonomia: A Case Report and Review of ManagementNishant Sharma0Si Li1Metlapalli Venkata Sravanthi2Dan Kazmierski3Yichen Wang4Amit Sharma5Pragya Dhaubhadel6The Wright Center for Graduate Medical Education, 501 South Washington Avenue, Scranton, PA 18505, USAThe Wright Center for Graduate Medical Education, 501 South Washington Avenue, Scranton, PA 18505, USAThe Wright Center for Graduate Medical Education, 501 South Washington Avenue, Scranton, PA 18505, USAThe Wright Center for Graduate Medical Education, 501 South Washington Avenue, Scranton, PA 18505, USAThe Wright Center for Graduate Medical Education, 501 South Washington Avenue, Scranton, PA 18505, USAGeisinger Community Medical Center, 1800 Mulberry Street, Scranton, PA 18510, USAGeisinger Community Medical Center, 1800 Mulberry Street, Scranton, PA 18510, USATetanus is a life-threatening infectious neurological disorder that is now a rare disease due to the institution of wide-spread vaccination strategies. We present an uncommon case of generalized severe tetanus with consequent respiratory failure requiring mechanical ventilation, which was associated with dysautonomia. A 20-year-old unvaccinated female presented with neck stiffness and diffuse muscle spasms following a laceration sustained 3 weeks prior. She was admitted to the intensive care unit for mechanical ventilation and was treated with immunoglobulin, tetanus toxoid, metronidazole, and high doses of sedatives. She also developed dysautonomia, with alternating bradycardia and tachycardia, as well as fluctuating blood pressure. She was successfully extubated and discharged. We also review the epidemiology, pathophysiology, and management of tetanus and discuss dysautonomia in the setting of tetanus.http://dx.doi.org/10.1155/2021/8842522 |
| spellingShingle | Nishant Sharma Si Li Metlapalli Venkata Sravanthi Dan Kazmierski Yichen Wang Amit Sharma Pragya Dhaubhadel Tetanus Complicated by Dysautonomia: A Case Report and Review of Management Case Reports in Critical Care |
| title | Tetanus Complicated by Dysautonomia: A Case Report and Review of Management |
| title_full | Tetanus Complicated by Dysautonomia: A Case Report and Review of Management |
| title_fullStr | Tetanus Complicated by Dysautonomia: A Case Report and Review of Management |
| title_full_unstemmed | Tetanus Complicated by Dysautonomia: A Case Report and Review of Management |
| title_short | Tetanus Complicated by Dysautonomia: A Case Report and Review of Management |
| title_sort | tetanus complicated by dysautonomia a case report and review of management |
| url | http://dx.doi.org/10.1155/2021/8842522 |
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