Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure

Objective. To describe a single surgeon’s experience utilizing prompt primary slow-burn transscleral cyclophotocoagulation (CPC) with prior or concurrent anti-VEGF and subsequent aqueous shunt as needed in NVG eyes with near-total synechial angle closure at presentation. Methods. Retrospective chart...

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Main Authors: Jessie Wang, Lindsay Y. Chun, Mary Qiu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2023/5719002
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author Jessie Wang
Lindsay Y. Chun
Mary Qiu
author_facet Jessie Wang
Lindsay Y. Chun
Mary Qiu
author_sort Jessie Wang
collection DOAJ
description Objective. To describe a single surgeon’s experience utilizing prompt primary slow-burn transscleral cyclophotocoagulation (CPC) with prior or concurrent anti-VEGF and subsequent aqueous shunt as needed in NVG eyes with near-total synechial angle closure at presentation. Methods. Retrospective chart review of all NVG patients with uncontrolled IOP, active anterior segment NV, near-total synechial angle closure, and no contraindications to prompt anti-VEGF who received CPC within 3 days of presentation with at least 6 months of follow-up. Results. Eight patients with mean age 60.6 years were included. Underlying etiologies were CRVO (N=3), PDR (N=2), CRAO (N=1), BRVO (N=1), and chronic RD (N=1). All eyes underwent CPC with intravitreal anti-VEGF within 3 days of presentation. Five patients did not require subsequent aqueous shunts through a mean follow-up of 15 months; most recent visual acuities ranged from 20/40 to LP, and IOPs ranged from 5 to 11 mmHg on 0 to 3 IOP-lowering medications. Three patients who required subsequent tubes had complete regression of active anterior segment NV at the time of surgery. Most recent visual acuities ranged from 20/100 to 20/125, and IOPs ranged from 8 to 14 mmHg on 0 meds at a mean follow-up of 10 months. No eyes developed uncontrolled inflammation, sympathetic ophthalmia, or phthisis. Conclusion. Prompt primary slow-burn CPC with prior or concurrent anti-VEGF may be an effective strategy to immediately lower IOP in acute NVG eyes with active anterior segment NV and near-total synechial angle closure. If IOP becomes uncontrolled later, an aqueous shunt can be implanted in a controlled setting after active anterior segment NV has regressed.
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spelling doaj-art-d51ae17b8b2f40dca8fea93d285ee7222025-02-03T06:45:38ZengWileyCase Reports in Ophthalmological Medicine2090-67302023-01-01202310.1155/2023/5719002Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle ClosureJessie Wang0Lindsay Y. Chun1Mary Qiu2Department of Ophthalmology & Visual ScienceDepartment of Ophthalmology & Visual ScienceDepartment of Ophthalmology & Visual ScienceObjective. To describe a single surgeon’s experience utilizing prompt primary slow-burn transscleral cyclophotocoagulation (CPC) with prior or concurrent anti-VEGF and subsequent aqueous shunt as needed in NVG eyes with near-total synechial angle closure at presentation. Methods. Retrospective chart review of all NVG patients with uncontrolled IOP, active anterior segment NV, near-total synechial angle closure, and no contraindications to prompt anti-VEGF who received CPC within 3 days of presentation with at least 6 months of follow-up. Results. Eight patients with mean age 60.6 years were included. Underlying etiologies were CRVO (N=3), PDR (N=2), CRAO (N=1), BRVO (N=1), and chronic RD (N=1). All eyes underwent CPC with intravitreal anti-VEGF within 3 days of presentation. Five patients did not require subsequent aqueous shunts through a mean follow-up of 15 months; most recent visual acuities ranged from 20/40 to LP, and IOPs ranged from 5 to 11 mmHg on 0 to 3 IOP-lowering medications. Three patients who required subsequent tubes had complete regression of active anterior segment NV at the time of surgery. Most recent visual acuities ranged from 20/100 to 20/125, and IOPs ranged from 8 to 14 mmHg on 0 meds at a mean follow-up of 10 months. No eyes developed uncontrolled inflammation, sympathetic ophthalmia, or phthisis. Conclusion. Prompt primary slow-burn CPC with prior or concurrent anti-VEGF may be an effective strategy to immediately lower IOP in acute NVG eyes with active anterior segment NV and near-total synechial angle closure. If IOP becomes uncontrolled later, an aqueous shunt can be implanted in a controlled setting after active anterior segment NV has regressed.http://dx.doi.org/10.1155/2023/5719002
spellingShingle Jessie Wang
Lindsay Y. Chun
Mary Qiu
Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
Case Reports in Ophthalmological Medicine
title Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
title_full Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
title_fullStr Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
title_full_unstemmed Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
title_short Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure
title_sort cyclophotocoagulation in neovascular glaucoma with near total synechial angle closure
url http://dx.doi.org/10.1155/2023/5719002
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AT lindsayychun cyclophotocoagulationinneovascularglaucomawithneartotalsynechialangleclosure
AT maryqiu cyclophotocoagulationinneovascularglaucomawithneartotalsynechialangleclosure