Role of mast cell in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

Role of mast cell in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

Abstract The pro-tumor effects of mast cell (MC) in the tumor microenvironment (TME) are becoming increasingly clear. Recently, MC were shown to contribute to tumor malignancy by supporting the migration of tumor-associated macrophages (TAMs), suggesting a relationship with tumor immunity. In the cu...

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Bibliographic Details
Main Authors: Masaaki Nishi, Shoko Yamashita, Chie Takasu, Yuma Wada, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Hideya Kashihara, Toshiaki Yoshimoto, Mitsuo Shimada
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Mast cell
Rectal cancer
Neoadjuvant chemoradiotherapy
Tumor associated macrophage
Online Access:https://doi.org/10.1186/s12885-025-13458-9
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