Good’s syndrome revealed by recurrent sigmoid diverticulitis
Thymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia gravis. Good’s syndrome (GS) is an acquired a...
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2025-06-01
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| Series: | European Journal of Case Reports in Internal Medicine |
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| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/5480 |
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| author | Hassene Attout Jade Constant Amel Abdelatif Guillaume Barry Olivier Halle |
| author_facet | Hassene Attout Jade Constant Amel Abdelatif Guillaume Barry Olivier Halle |
| author_sort | Hassene Attout |
| collection | DOAJ |
| description | Thymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia gravis. Good’s syndrome (GS) is an acquired adult-onset combined immunodeficiency typically characterised by the triad of thymoma, hypogammaglobulinaemia and increased susceptibility to recurrent infections. Immunoglobulin replacement is the main therapeutic strategy. Our knowledge of thymoma-associated immunodeficiency is predominantly derived from case reports or small series. We report the case of a patient with recurrent sigmoid diverticulitis that appeared after a thymectomy, who was subsequently found to have severe hypogammaglobulinaemia. |
| format | Article |
| id | doaj-art-d4e7b282fb8b4278adfd4d126b853708 |
| institution | Kabale University |
| issn | 2284-2594 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-d4e7b282fb8b4278adfd4d126b8537082025-08-20T03:28:43ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-06-0110.12890/2025_0054805015Good’s syndrome revealed by recurrent sigmoid diverticulitisHassene Attout0Jade Constant1Amel Abdelatif2Guillaume Barry3Olivier Halle4Internal Medicine Department, Les Cevennes Hospital, Alès, FranceInternal Medicine Department, Les Cevennes Hospital, Alès, FranceInternal Medicine Department, Les Cevennes Hospital, Alès, FranceInternal Medicine Department, Les Cevennes Hospital, Alès, FranceInternal Medicine Department, Les Cevennes Hospital, Alès, FranceThymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia gravis. Good’s syndrome (GS) is an acquired adult-onset combined immunodeficiency typically characterised by the triad of thymoma, hypogammaglobulinaemia and increased susceptibility to recurrent infections. Immunoglobulin replacement is the main therapeutic strategy. Our knowledge of thymoma-associated immunodeficiency is predominantly derived from case reports or small series. We report the case of a patient with recurrent sigmoid diverticulitis that appeared after a thymectomy, who was subsequently found to have severe hypogammaglobulinaemia.https://www.ejcrim.com/index.php/EJCRIM/article/view/5480good’s syndromethymomahypogammaglobulinaemia |
| spellingShingle | Hassene Attout Jade Constant Amel Abdelatif Guillaume Barry Olivier Halle Good’s syndrome revealed by recurrent sigmoid diverticulitis European Journal of Case Reports in Internal Medicine good’s syndrome thymoma hypogammaglobulinaemia |
| title | Good’s syndrome revealed by recurrent sigmoid diverticulitis |
| title_full | Good’s syndrome revealed by recurrent sigmoid diverticulitis |
| title_fullStr | Good’s syndrome revealed by recurrent sigmoid diverticulitis |
| title_full_unstemmed | Good’s syndrome revealed by recurrent sigmoid diverticulitis |
| title_short | Good’s syndrome revealed by recurrent sigmoid diverticulitis |
| title_sort | good s syndrome revealed by recurrent sigmoid diverticulitis |
| topic | good’s syndrome thymoma hypogammaglobulinaemia |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/5480 |
| work_keys_str_mv | AT hasseneattout goodssyndromerevealedbyrecurrentsigmoiddiverticulitis AT jadeconstant goodssyndromerevealedbyrecurrentsigmoiddiverticulitis AT amelabdelatif goodssyndromerevealedbyrecurrentsigmoiddiverticulitis AT guillaumebarry goodssyndromerevealedbyrecurrentsigmoiddiverticulitis AT olivierhalle goodssyndromerevealedbyrecurrentsigmoiddiverticulitis |