Medication adherence and non-adherence in arterial hypertension: a narrative review
Systemic hypertension, a significant global health issue and a leading risk factor for cardiovascular mortality affects half of the adult population, with increasing prevalence notably in low- and middle-income countries. Despite advancements in diagnosis and treatment, only one in four individuals...
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Open Exploration Publishing Inc.
2025-01-01
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| Series: | Exploration of Medicine |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A1001276/1001276.pdf |
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| author | Claudio Tomasino Marco Tomasino |
| author_facet | Claudio Tomasino Marco Tomasino |
| author_sort | Claudio Tomasino |
| collection | DOAJ |
| description | Systemic hypertension, a significant global health issue and a leading risk factor for cardiovascular mortality affects half of the adult population, with increasing prevalence notably in low- and middle-income countries. Despite advancements in diagnosis and treatment, only one in four individuals with hypertension achieve satisfactory control over their condition. Medication adherence, critical for effective hypertension management, is complex and multifaceted. Non-adherence, encompassing late or non-initiation, sub-optimal implementation, and early discontinuation of treatment, is prevalent worldwide, with reported rates of anti-hypertensive medication non-adherence ranging from 30% to 40%. Adherence is influenced by various factors including drug regimen complexity, patient education, and socioeconomic status. Poor adherence is linked to increased cardiovascular risks and is compounded by clinical inertia among physicians. Addressing barriers to adherence and implementing evidence-based interventions can significantly reduce the global burden of hypertension and its associated complications. This review highlighted the critical need for improved adherence strategies to enhance hypertension management. It focused on novel tools such as mobile health interventions and regimen-simplification through single-pill combinations, which can improve treatment persistence and blood pressure control. |
| format | Article |
| id | doaj-art-d4e2cee833a9457eb5674225f0552a13 |
| institution | Kabale University |
| issn | 2692-3106 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Medicine |
| spelling | doaj-art-d4e2cee833a9457eb5674225f0552a132025-01-26T08:32:27ZengOpen Exploration Publishing Inc.Exploration of Medicine2692-31062025-01-016100127610.37349/emed.2025.1001276Medication adherence and non-adherence in arterial hypertension: a narrative reviewClaudio Tomasino0https://orcid.org/0009-0000-3683-9666Marco Tomasino1https://orcid.org/0000-0003-1989-4342Division of Cardiology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE) “G. D’Alessandro”, University Hospital Paolo Giaccone, University of Palermo, 90100 Palermo, ItalyCardiology Department, Hospital Universitari Vall D’Hebron, 08031 Barcelona, SpainSystemic hypertension, a significant global health issue and a leading risk factor for cardiovascular mortality affects half of the adult population, with increasing prevalence notably in low- and middle-income countries. Despite advancements in diagnosis and treatment, only one in four individuals with hypertension achieve satisfactory control over their condition. Medication adherence, critical for effective hypertension management, is complex and multifaceted. Non-adherence, encompassing late or non-initiation, sub-optimal implementation, and early discontinuation of treatment, is prevalent worldwide, with reported rates of anti-hypertensive medication non-adherence ranging from 30% to 40%. Adherence is influenced by various factors including drug regimen complexity, patient education, and socioeconomic status. Poor adherence is linked to increased cardiovascular risks and is compounded by clinical inertia among physicians. Addressing barriers to adherence and implementing evidence-based interventions can significantly reduce the global burden of hypertension and its associated complications. This review highlighted the critical need for improved adherence strategies to enhance hypertension management. It focused on novel tools such as mobile health interventions and regimen-simplification through single-pill combinations, which can improve treatment persistence and blood pressure control.https://www.explorationpub.com/uploads/Article/A1001276/1001276.pdfadherencenon-adherencearterialhypertensionnarrative review |
| spellingShingle | Claudio Tomasino Marco Tomasino Medication adherence and non-adherence in arterial hypertension: a narrative review Exploration of Medicine adherence non-adherence arterial hypertension narrative review |
| title | Medication adherence and non-adherence in arterial hypertension: a narrative review |
| title_full | Medication adherence and non-adherence in arterial hypertension: a narrative review |
| title_fullStr | Medication adherence and non-adherence in arterial hypertension: a narrative review |
| title_full_unstemmed | Medication adherence and non-adherence in arterial hypertension: a narrative review |
| title_short | Medication adherence and non-adherence in arterial hypertension: a narrative review |
| title_sort | medication adherence and non adherence in arterial hypertension a narrative review |
| topic | adherence non-adherence arterial hypertension narrative review |
| url | https://www.explorationpub.com/uploads/Article/A1001276/1001276.pdf |
| work_keys_str_mv | AT claudiotomasino medicationadherenceandnonadherenceinarterialhypertensionanarrativereview AT marcotomasino medicationadherenceandnonadherenceinarterialhypertensionanarrativereview |