Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19

Trichosporon asahii is a yeast-like basidiomycete that is an emerging opportunistic infection in immunocompromised patients. Urinary tract infections due to T. asahii are rarely reported in the literature and typically seen only in immunocompromised patients. In addition to being immunocompromised,...

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Main Authors: Verschoyle Cronyn, John Howard, Leslie Chiang, Lisa Le, Zandraetta Tims-Cook, Alida M Gertz
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/6841393
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author Verschoyle Cronyn
John Howard
Leslie Chiang
Lisa Le
Zandraetta Tims-Cook
Alida M Gertz
author_facet Verschoyle Cronyn
John Howard
Leslie Chiang
Lisa Le
Zandraetta Tims-Cook
Alida M Gertz
author_sort Verschoyle Cronyn
collection DOAJ
description Trichosporon asahii is a yeast-like basidiomycete that is an emerging opportunistic infection in immunocompromised patients. Urinary tract infections due to T. asahii are rarely reported in the literature and typically seen only in immunocompromised patients. In addition to being immunocompromised, critically ill COVID-19 patients often have prolonged exposure to antibiotics, corticosteroids, and Foley catheters, which further increases their susceptibility to infection with T. asahii. There are limited case reports documenting successful treatment of T. asahii among hospitalized patients, particularly among COVID-19 patients, in the literature. Therefore, it is important that successful treatment regimens be reported. Here, we report a case of T. asahii urinary tract infection successfully treated with fluconazole and voriconazole in a 73-year-old male recovering from COVID-19. Urinary tract infections with T. asahii should be considered in persistently febrile COVID-19 patients with fungal urinary tract infections since prompt recognition and treatment can reduce the risk of disseminated disease and early mortality.
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spelling doaj-art-d4caefe68e7242eb857c07d727ee52d82025-02-03T01:31:34ZengWileyCase Reports in Infectious Diseases2090-66332021-01-01202110.1155/2021/6841393Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19Verschoyle Cronyn0John Howard1Leslie Chiang2Lisa Le3Zandraetta Tims-Cook4Alida M Gertz5Wellstar Atlanta Medical Center Family Med Residency ProgramMedical College of GeorgiaWellstar Atlanta Medical Center Family Med Residency ProgramWellstar Atlanta Medical Center Family Med Residency ProgramWellstar Atlanta Medical Center Family Med Residency ProgramWellstar Atlanta Medical Center Family Med Residency ProgramTrichosporon asahii is a yeast-like basidiomycete that is an emerging opportunistic infection in immunocompromised patients. Urinary tract infections due to T. asahii are rarely reported in the literature and typically seen only in immunocompromised patients. In addition to being immunocompromised, critically ill COVID-19 patients often have prolonged exposure to antibiotics, corticosteroids, and Foley catheters, which further increases their susceptibility to infection with T. asahii. There are limited case reports documenting successful treatment of T. asahii among hospitalized patients, particularly among COVID-19 patients, in the literature. Therefore, it is important that successful treatment regimens be reported. Here, we report a case of T. asahii urinary tract infection successfully treated with fluconazole and voriconazole in a 73-year-old male recovering from COVID-19. Urinary tract infections with T. asahii should be considered in persistently febrile COVID-19 patients with fungal urinary tract infections since prompt recognition and treatment can reduce the risk of disseminated disease and early mortality.http://dx.doi.org/10.1155/2021/6841393
spellingShingle Verschoyle Cronyn
John Howard
Leslie Chiang
Lisa Le
Zandraetta Tims-Cook
Alida M Gertz
Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
Case Reports in Infectious Diseases
title Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
title_full Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
title_fullStr Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
title_full_unstemmed Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
title_short Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19
title_sort trichosporon asahii urinary tract infection in a patient with severe covid 19
url http://dx.doi.org/10.1155/2021/6841393
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AT lisale trichosporonasahiiurinarytractinfectioninapatientwithseverecovid19
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