Cellular and Molecular Changes in Orthodontic Tooth Movement
Tooth movement induced by orthodontic treatment can cause sequential reactions involving the periodontal tissue and alveolar bone, resulting in the release of numerous substances from the dental tissues and surrounding structures. To better understand the biological processes involved in orthodontic...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2011/761768 |
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| author | Shahrul Hisham Zainal Ariffin Zulham Yamamoto lntan Zarina Zainol Abidin Rohaya Megat Abdul Wahab Zaidah Zainal Ariffin |
| author_facet | Shahrul Hisham Zainal Ariffin Zulham Yamamoto lntan Zarina Zainol Abidin Rohaya Megat Abdul Wahab Zaidah Zainal Ariffin |
| author_sort | Shahrul Hisham Zainal Ariffin |
| collection | DOAJ |
| description | Tooth movement induced by orthodontic treatment can cause sequential reactions involving the periodontal tissue and alveolar bone, resulting in the release of numerous substances from the dental tissues and surrounding structures. To better understand the biological processes involved in orthodontic treatment, improve treatment, and reduce adverse side effects, several of these substances have been proposed as biomarkers. Potential biological markers can be collected from different tissue samples, and suitable sampling is important to accurately reflect biological processes. This paper covers the tissue changes that are involved during orthodontic tooth movement such as at compression region (involving osteoblasts), tension region (involving osteoclasts), dental root, and pulp tissues. Besides, the involvement of stem cells and their development towards osteoblasts and osteoclasts during orthodontic treatment have also been explained. Several possible biomarkers representing these biological changes during specific phenomenon, that is, bone remodelling (formation and resorption), inflammation, and root resorption have also been proposed. The knowledge of these biomarkers could be used in accelerating orthodontic treatment. |
| format | Article |
| id | doaj-art-d483eb04ab1c4cf5bd01fe55af645cc6 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-d483eb04ab1c4cf5bd01fe55af645cc62025-02-03T05:49:35ZengWileyThe Scientific World Journal1537-744X2011-01-01111788180310.1100/2011/761768761768Cellular and Molecular Changes in Orthodontic Tooth MovementShahrul Hisham Zainal Ariffin0Zulham Yamamoto1lntan Zarina Zainol Abidin2Rohaya Megat Abdul Wahab3Zaidah Zainal Ariffin4School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, MalaysiaSchool of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, MalaysiaSchool of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, MalaysiaDepartment of Orthodontics, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, MalaysiaDepartment of Microbiology, Faculty of Applied Science, Universiti Teknologi MARA, 40450 Shah Alam, MalaysiaTooth movement induced by orthodontic treatment can cause sequential reactions involving the periodontal tissue and alveolar bone, resulting in the release of numerous substances from the dental tissues and surrounding structures. To better understand the biological processes involved in orthodontic treatment, improve treatment, and reduce adverse side effects, several of these substances have been proposed as biomarkers. Potential biological markers can be collected from different tissue samples, and suitable sampling is important to accurately reflect biological processes. This paper covers the tissue changes that are involved during orthodontic tooth movement such as at compression region (involving osteoblasts), tension region (involving osteoclasts), dental root, and pulp tissues. Besides, the involvement of stem cells and their development towards osteoblasts and osteoclasts during orthodontic treatment have also been explained. Several possible biomarkers representing these biological changes during specific phenomenon, that is, bone remodelling (formation and resorption), inflammation, and root resorption have also been proposed. The knowledge of these biomarkers could be used in accelerating orthodontic treatment.http://dx.doi.org/10.1100/2011/761768 |
| spellingShingle | Shahrul Hisham Zainal Ariffin Zulham Yamamoto lntan Zarina Zainol Abidin Rohaya Megat Abdul Wahab Zaidah Zainal Ariffin Cellular and Molecular Changes in Orthodontic Tooth Movement The Scientific World Journal |
| title | Cellular and Molecular Changes in Orthodontic Tooth Movement |
| title_full | Cellular and Molecular Changes in Orthodontic Tooth Movement |
| title_fullStr | Cellular and Molecular Changes in Orthodontic Tooth Movement |
| title_full_unstemmed | Cellular and Molecular Changes in Orthodontic Tooth Movement |
| title_short | Cellular and Molecular Changes in Orthodontic Tooth Movement |
| title_sort | cellular and molecular changes in orthodontic tooth movement |
| url | http://dx.doi.org/10.1100/2011/761768 |
| work_keys_str_mv | AT shahrulhishamzainalariffin cellularandmolecularchangesinorthodontictoothmovement AT zulhamyamamoto cellularandmolecularchangesinorthodontictoothmovement AT lntanzarinazainolabidin cellularandmolecularchangesinorthodontictoothmovement AT rohayamegatabdulwahab cellularandmolecularchangesinorthodontictoothmovement AT zaidahzainalariffin cellularandmolecularchangesinorthodontictoothmovement |