A division-dependent compartmental model for computing cell numbers in CFSE-based lymphocyte proliferation assays

Some key features of a mathematical description of an immune response are an estimate of the number of responding cells and the manner in which those cells divide, differentiate, and die. The intracellular dye CFSE is a powerful experimental tool for the analysis of a population of dividing cells,...

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Bibliographic Details
Main Authors: H. Thomas Banks, W. Clayton Thompson, Cristina Peligero, Sandra Giest, Jordi Argilaguet, Andreas Meyerhans
Format: Article
Language:English
Published: AIMS Press 2012-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.699
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