Machine learning-powered, high-affinity modification strategies for aptamers
The binding affinity of aptamers to targets has a crucial role in the pharmaceutical and biosensing effects. Despite diverse post-systematic evolution of ligands by exponential enrichment (post-SELEX) modifications explored in aptamer optimization, accurate prediction of high-affinity modification s...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Compuscript Ltd
2025-01-01
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Series: | Acta Materia Medica |
Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0065 |
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