Synovial Fluid Extracellular Vesicles from Patients with Severe Osteoarthritis Differentially Promote a Pro-Catabolic, Inflammatory Chondrocyte Phenotype
Synovial inflammation is recognised as a pathological driver of osteoarthritis (OA), a degenerative joint disease involving cartilage degradation and joint pain. Since extracellular vesicles (EVs) have emerged as key mediators of cellular cross-talk, this study characterised synovial fluid EVs (SFEV...
Saved in:
| Main Authors: | Caitlin Ditchfield, Joshua Price, Edward T. Davis, Simon W. Jones |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/15/6/829 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Single-cell profiling uncovers synovial fibroblast subpopulations associated with chondrocyte injury in osteoarthritis
by: Zezhong Liu, et al.
Published: (2024-12-01) -
The communication role of extracellular vesicles in the osteoarthritis microenvironment
by: Pu Chen, et al.
Published: (2025-03-01) -
Unveiling the potential of MSC extracellular vesicles: MiR-122-5p enhancing chondrocyte regeneration in osteoarthritis via autophagy mechanism
by: Haifeng Zhang, et al.
Published: (2025-06-01) -
Synovitis in osteoarthritis: the current state of the problem
by: I. S. Dydykina, et al.
Published: (2021-04-01) -
Synovial Fluid Markers and Extracellular Vesicles in Rheumatoid Arthritis
by: Veronika Smolinska, et al.
Published: (2024-11-01)