Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy

Fournier's gangrene is a rare process which affects soft tissue in the genital and perirectal area. It can also progress to all different stages of sepsis, and abdominal compartment syndrome can be one of its complications. Two patients in septic shock due to Fournier gangrene were admitted to...

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Main Authors: Giovanni Zagli, Giovanni Cianchi, Sara Degl'Innocenti, Jessyca Parodo, Lorenzo Bonetti, Paolo Prosperi, Adriano Peris
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2011/430983
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author Giovanni Zagli
Giovanni Cianchi
Sara Degl'Innocenti
Jessyca Parodo
Lorenzo Bonetti
Paolo Prosperi
Adriano Peris
author_facet Giovanni Zagli
Giovanni Cianchi
Sara Degl'Innocenti
Jessyca Parodo
Lorenzo Bonetti
Paolo Prosperi
Adriano Peris
author_sort Giovanni Zagli
collection DOAJ
description Fournier's gangrene is a rare process which affects soft tissue in the genital and perirectal area. It can also progress to all different stages of sepsis, and abdominal compartment syndrome can be one of its complications. Two patients in septic shock due to Fournier gangrene were admitted to the Intensive Care Unit of Emergency Department. In both cases, infection started from the scrotum and the necrosis quickly involved genitals, perineal, and inguinal regions. Patients were treated with surgical debridement, protective colostomy, hyperbaric oxygen therapy, and broad-spectrum antibacterial chemotherapy. Vacuum-assisted closure (VAC) therapy was applied to the wound with the aim to clean, decontaminate, and avoid abdominal compartmental syndrome development. Both patients survived and were discharged from Intensive Care Unit after hyperbaric oxygen therapy cycles and abdominal closure.
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series Case Reports in Anesthesiology
spelling doaj-art-d447826b230c4ab883dc2b1e98f625992025-02-03T01:00:02ZengWileyCase Reports in Anesthesiology2090-63822090-63902011-01-01201110.1155/2011/430983430983Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective ColostomyGiovanni Zagli0Giovanni Cianchi1Sara Degl'Innocenti2Jessyca Parodo3Lorenzo Bonetti4Paolo Prosperi5Adriano Peris6Anaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyAnaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyAnaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyAnaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyAnaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of General Surgery, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyAnaesthesia and Intensive Care Unit of Emergency Department, Careggi Teaching Hospital, Largo Brambilla 3, 50134 Florence, ItalyFournier's gangrene is a rare process which affects soft tissue in the genital and perirectal area. It can also progress to all different stages of sepsis, and abdominal compartment syndrome can be one of its complications. Two patients in septic shock due to Fournier gangrene were admitted to the Intensive Care Unit of Emergency Department. In both cases, infection started from the scrotum and the necrosis quickly involved genitals, perineal, and inguinal regions. Patients were treated with surgical debridement, protective colostomy, hyperbaric oxygen therapy, and broad-spectrum antibacterial chemotherapy. Vacuum-assisted closure (VAC) therapy was applied to the wound with the aim to clean, decontaminate, and avoid abdominal compartmental syndrome development. Both patients survived and were discharged from Intensive Care Unit after hyperbaric oxygen therapy cycles and abdominal closure.http://dx.doi.org/10.1155/2011/430983
spellingShingle Giovanni Zagli
Giovanni Cianchi
Sara Degl'Innocenti
Jessyca Parodo
Lorenzo Bonetti
Paolo Prosperi
Adriano Peris
Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
Case Reports in Anesthesiology
title Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
title_full Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
title_fullStr Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
title_full_unstemmed Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
title_short Treatment of Fournier's Gangrene with Combination of Vacuum-Assisted Closure Therapy, Hyperbaric Oxygen Therapy, and Protective Colostomy
title_sort treatment of fournier s gangrene with combination of vacuum assisted closure therapy hyperbaric oxygen therapy and protective colostomy
url http://dx.doi.org/10.1155/2011/430983
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