Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy?
An increase in the prevalence of obesity in people with spinal cord injury can contribute to low-grade chronic inflammation and increase the risk of infection in this population. A decrease in sympathetic activity contributes to immunosuppression due to the lower activation of immune cells in the bl...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2013/971841 |
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| _version_ | 1832554389144862720 |
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| author | Eduardo da Silva Alves Valdir de Aquino Lemos Francieli Ruiz da Silva Fabio Santos Lira Ronaldo Vagner Thomathieli dos Santos João Paulo Pereira Rosa Erico Caperuto Sergio Tufik Marco Tulio de Mello |
| author_facet | Eduardo da Silva Alves Valdir de Aquino Lemos Francieli Ruiz da Silva Fabio Santos Lira Ronaldo Vagner Thomathieli dos Santos João Paulo Pereira Rosa Erico Caperuto Sergio Tufik Marco Tulio de Mello |
| author_sort | Eduardo da Silva Alves |
| collection | DOAJ |
| description | An increase in the prevalence of obesity in people with spinal cord injury can contribute to low-grade chronic inflammation and increase the risk of infection in this population. A decrease in sympathetic activity contributes to immunosuppression due to the lower activation of immune cells in the blood. The effects of physical exercise on inflammatory parameters in individuals with spinal cord injury have not been well described. We conducted a review of the literature published from 1974 to 2012. This review explored the relationships between low-grade inflammation, spinal cord injury, and exercise to discuss a novel mechanism that might explain the beneficial effects of exercise involving an increase in catecholamines and cytokines in people with spinal cord injury. |
| format | Article |
| id | doaj-art-d43d80bea9f94eb5b03c457e00599b4a |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-d43d80bea9f94eb5b03c457e00599b4a2025-02-03T05:51:40ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/971841971841Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy?Eduardo da Silva Alves0Valdir de Aquino Lemos1Francieli Ruiz da Silva2Fabio Santos Lira3Ronaldo Vagner Thomathieli dos Santos4João Paulo Pereira Rosa5Erico Caperuto6Sergio Tufik7Marco Tulio de Mello8Departamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilDepartamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilDepartamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilCentro de Estudos em Psicobiologia e Exercício, (CEPE), 04020-050 São Paulo, BrazilDepartamento de Biociências, Universidade Federal de São Paulo, UNIFESP, Campus da Baixada Santista, BrazilDepartamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilLaboratório do Movimento Humano, Universidade São Judas Tadeu, 04020-050 São Paulo, BrazilDepartamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilDepartamento de Psicobiologia, Universidade Federal de São Paulo, UNIFESP, Campus São Paulo, 04020-050 São Paulo, BrazilAn increase in the prevalence of obesity in people with spinal cord injury can contribute to low-grade chronic inflammation and increase the risk of infection in this population. A decrease in sympathetic activity contributes to immunosuppression due to the lower activation of immune cells in the blood. The effects of physical exercise on inflammatory parameters in individuals with spinal cord injury have not been well described. We conducted a review of the literature published from 1974 to 2012. This review explored the relationships between low-grade inflammation, spinal cord injury, and exercise to discuss a novel mechanism that might explain the beneficial effects of exercise involving an increase in catecholamines and cytokines in people with spinal cord injury.http://dx.doi.org/10.1155/2013/971841 |
| spellingShingle | Eduardo da Silva Alves Valdir de Aquino Lemos Francieli Ruiz da Silva Fabio Santos Lira Ronaldo Vagner Thomathieli dos Santos João Paulo Pereira Rosa Erico Caperuto Sergio Tufik Marco Tulio de Mello Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? Mediators of Inflammation |
| title | Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? |
| title_full | Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? |
| title_fullStr | Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? |
| title_full_unstemmed | Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? |
| title_short | Low-Grade Inflammation and Spinal Cord Injury: Exercise as Therapy? |
| title_sort | low grade inflammation and spinal cord injury exercise as therapy |
| url | http://dx.doi.org/10.1155/2013/971841 |
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