Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review
Introduction: Malignant mixed Müllerian tumors (MMMT), also known as carcinosarcomas, are rare and highly aggressive neoplasms of the uterus, accounting for less than 5% of all uterine malignancies. These tumors are biphasic, comprising both carcinomatous (epithelial) and sarcomatous (mesenchymal) c...
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Albanian Society for Trauma and Emergency Surgery
2025-01-01
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| Series: | Albanian Journal of Trauma and Emergency Surgery |
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| Online Access: | http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/433 |
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| author | Leon Kaza Leart Berdica Teona Teona Albina Ndoja |
| author_facet | Leon Kaza Leart Berdica Teona Teona Albina Ndoja |
| author_sort | Leon Kaza |
| collection | DOAJ |
| description | Introduction: Malignant mixed Müllerian tumors (MMMT), also known as carcinosarcomas, are rare and highly aggressive neoplasms of the uterus, accounting for less than 5% of all uterine malignancies. These tumors are biphasic, comprising both carcinomatous (epithelial) and sarcomatous (mesenchymal) components, and are typically associated with poor prognoses due to their rapid progression and high metastatic potential.
In this report, we present a unique case of noninvasive polypoid MMMT of the uterus, highlighting its clinical presentation, diagnostic challenges, and management. We also provide a comprehensive literature review, which enriches our understanding of this case within the broader context of uterine carcinosarcomas.
Results: This is the first documented case in English literature of a polypoid uterine carcinosarcoma without endometrial infiltration. It is significant because it adds to the limited literature on noninvasive polypoid MMMTs, typically aggressive and diagnosed at advanced stages. Uterine carcinosarcomas are generally aggressive, with most cases diagnosed at advanced stages.
Conclusion: Uterine carcinosarcomas are indeed rare, aggressive, and rapidly progressing neoplasms with poor prognoses. It is crucial to include carcinosarcomas in the differential diagnosis of high-grade uterine neoplasms, especially for polypoid tumors. This inclusion is not just essential, but it is the key to ensuring accurate and timely diagnosis, underscoring the significant role of medical professionals in this process.
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| format | Article |
| id | doaj-art-d4307f0cf1944528a9678906694a02ac |
| institution | Kabale University |
| issn | 2521-8778 2616-4922 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Albanian Society for Trauma and Emergency Surgery |
| record_format | Article |
| series | Albanian Journal of Trauma and Emergency Surgery |
| spelling | doaj-art-d4307f0cf1944528a9678906694a02ac2025-01-19T14:24:40ZengAlbanian Society for Trauma and Emergency SurgeryAlbanian Journal of Trauma and Emergency Surgery2521-87782616-49222025-01-019110.32391/ajtes.v9i1.433Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature ReviewLeon Kaza0Leart Berdica1Teona Teona2Albina Ndoja3Lezha Regional Hospital, AlbaniaUniversity of Medicine of Tirana, AlbaniaUniversity of Medicine of Tirana, AlbaniaWestern Balkans University, Tirana, AlbaniaIntroduction: Malignant mixed Müllerian tumors (MMMT), also known as carcinosarcomas, are rare and highly aggressive neoplasms of the uterus, accounting for less than 5% of all uterine malignancies. These tumors are biphasic, comprising both carcinomatous (epithelial) and sarcomatous (mesenchymal) components, and are typically associated with poor prognoses due to their rapid progression and high metastatic potential. In this report, we present a unique case of noninvasive polypoid MMMT of the uterus, highlighting its clinical presentation, diagnostic challenges, and management. We also provide a comprehensive literature review, which enriches our understanding of this case within the broader context of uterine carcinosarcomas. Results: This is the first documented case in English literature of a polypoid uterine carcinosarcoma without endometrial infiltration. It is significant because it adds to the limited literature on noninvasive polypoid MMMTs, typically aggressive and diagnosed at advanced stages. Uterine carcinosarcomas are generally aggressive, with most cases diagnosed at advanced stages. Conclusion: Uterine carcinosarcomas are indeed rare, aggressive, and rapidly progressing neoplasms with poor prognoses. It is crucial to include carcinosarcomas in the differential diagnosis of high-grade uterine neoplasms, especially for polypoid tumors. This inclusion is not just essential, but it is the key to ensuring accurate and timely diagnosis, underscoring the significant role of medical professionals in this process. http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/433Noninvasive polypoid MMMTuterine carcinosarcomaendometrial neoplasmspolypoid uterine tumors |
| spellingShingle | Leon Kaza Leart Berdica Teona Teona Albina Ndoja Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review Albanian Journal of Trauma and Emergency Surgery Noninvasive polypoid MMMT uterine carcinosarcoma endometrial neoplasms polypoid uterine tumors |
| title | Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review |
| title_full | Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review |
| title_fullStr | Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review |
| title_full_unstemmed | Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review |
| title_short | Noninvasive Polypoid Malignant Mixed Mullerian Tumor of the Uterus: A Case Report and Literature Review |
| title_sort | noninvasive polypoid malignant mixed mullerian tumor of the uterus a case report and literature review |
| topic | Noninvasive polypoid MMMT uterine carcinosarcoma endometrial neoplasms polypoid uterine tumors |
| url | http://journal.astes.org.al/AJTES/index.php/AJTES/article/view/433 |
| work_keys_str_mv | AT leonkaza noninvasivepolypoidmalignantmixedmulleriantumoroftheuterusacasereportandliteraturereview AT leartberdica noninvasivepolypoidmalignantmixedmulleriantumoroftheuterusacasereportandliteraturereview AT teonateona noninvasivepolypoidmalignantmixedmulleriantumoroftheuterusacasereportandliteraturereview AT albinandoja noninvasivepolypoidmalignantmixedmulleriantumoroftheuterusacasereportandliteraturereview |