Hyperhomocysteinemia in a Patient with Moyamoya Disease

Moyamoya disease is a chronic progressive cerebrovascular disease characterized by bilateral occlusion or stenosis of arteries around circle of Willis. We report a case of 18-year-old female presented with recurrent episodes of headache and vertigo. On cerebral angiography, the patient was diagnosed...

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Main Authors: Durga Shankar Meena, Gopal Krishana Bohra, Mahadev Meena, Bharat Kumar Maheshwari
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2018/7806873
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author Durga Shankar Meena
Gopal Krishana Bohra
Mahadev Meena
Bharat Kumar Maheshwari
author_facet Durga Shankar Meena
Gopal Krishana Bohra
Mahadev Meena
Bharat Kumar Maheshwari
author_sort Durga Shankar Meena
collection DOAJ
description Moyamoya disease is a chronic progressive cerebrovascular disease characterized by bilateral occlusion or stenosis of arteries around circle of Willis. We report a case of 18-year-old female presented with recurrent episodes of headache and vertigo. On cerebral angiography, the patient was diagnosed to have moyamoya disease. On further evaluation, thrombophilia profile showed increased homocysteine level. The patient was treated conservatively with cobalamin and aspirin and advised for revascularization. According to the literature, there are few case reports of moyamoya disease with thrombotic disorders. Hence, we are reporting this interesting and rare case.
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institution Kabale University
issn 2090-6668
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publishDate 2018-01-01
publisher Wiley
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series Case Reports in Neurological Medicine
spelling doaj-art-d413b7feb5954b6e9e406477c77c878c2025-02-03T00:59:27ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/78068737806873Hyperhomocysteinemia in a Patient with Moyamoya DiseaseDurga Shankar Meena0Gopal Krishana Bohra1Mahadev Meena2Bharat Kumar Maheshwari3Department of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaMoyamoya disease is a chronic progressive cerebrovascular disease characterized by bilateral occlusion or stenosis of arteries around circle of Willis. We report a case of 18-year-old female presented with recurrent episodes of headache and vertigo. On cerebral angiography, the patient was diagnosed to have moyamoya disease. On further evaluation, thrombophilia profile showed increased homocysteine level. The patient was treated conservatively with cobalamin and aspirin and advised for revascularization. According to the literature, there are few case reports of moyamoya disease with thrombotic disorders. Hence, we are reporting this interesting and rare case.http://dx.doi.org/10.1155/2018/7806873
spellingShingle Durga Shankar Meena
Gopal Krishana Bohra
Mahadev Meena
Bharat Kumar Maheshwari
Hyperhomocysteinemia in a Patient with Moyamoya Disease
Case Reports in Neurological Medicine
title Hyperhomocysteinemia in a Patient with Moyamoya Disease
title_full Hyperhomocysteinemia in a Patient with Moyamoya Disease
title_fullStr Hyperhomocysteinemia in a Patient with Moyamoya Disease
title_full_unstemmed Hyperhomocysteinemia in a Patient with Moyamoya Disease
title_short Hyperhomocysteinemia in a Patient with Moyamoya Disease
title_sort hyperhomocysteinemia in a patient with moyamoya disease
url http://dx.doi.org/10.1155/2018/7806873
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AT gopalkrishanabohra hyperhomocysteinemiainapatientwithmoyamoyadisease
AT mahadevmeena hyperhomocysteinemiainapatientwithmoyamoyadisease
AT bharatkumarmaheshwari hyperhomocysteinemiainapatientwithmoyamoyadisease