Molecular Identification of Enterocytozoon bieneusi Isolates from Nigerian Children

A study was conducted to detect and identify enteric microsporidian species in 43 children from Oyo state, Nigeria. Using nested polymerase chain reaction, 9.3% of the children were identified as positive for Enterocytozoon bieneusi. DNA sequencing of the PCR products showed the presence of three kn...

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Bibliographic Details
Main Authors: Adekunle Bamidele Ayinmode, Oladele Teslim Ojuromi, Lihua Xiao
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2011/129542
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Summary:A study was conducted to detect and identify enteric microsporidian species in 43 children from Oyo state, Nigeria. Using nested polymerase chain reaction, 9.3% of the children were identified as positive for Enterocytozoon bieneusi. DNA sequencing of the PCR products showed the presence of three known genotypes (two isolates of genotype D and one of genotype K) and one new genotype. This study suggests that either human or animal (or both) could be the infection source for the children, since identified genotypes D and K have been previously detected in both immunocompromised and immunocompetent patients and domestic animals. The identification of high diversity also suggests intensive transmission of microsporidiosis in the studied area.
ISSN:2090-0023
2090-0031