Primary Bone Lymphoma: A Case Series and Review of Literature
Primary bone lymphoma (PBL) is a subtype of lymphoma that exclusively affects skeletal tissue. Despite the relatively common involvement of skeletal structures as a manifestation of non-Hodgkin’s lymphoma (NHL), primary and exclusive involvement of the skeletal system is rare. The prevalence of PBL...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2020/4254803 |
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| _version_ | 1832566163639369728 |
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| author | Poorva Bindal Aakash Desai Lukas Delasos Sudhanshu Mulay James Vredenburgh |
| author_facet | Poorva Bindal Aakash Desai Lukas Delasos Sudhanshu Mulay James Vredenburgh |
| author_sort | Poorva Bindal |
| collection | DOAJ |
| description | Primary bone lymphoma (PBL) is a subtype of lymphoma that exclusively affects skeletal tissue. Despite the relatively common involvement of skeletal structures as a manifestation of non-Hodgkin’s lymphoma (NHL), primary and exclusive involvement of the skeletal system is rare. The prevalence of PBL is estimated to be 3–7% amongst primary bone tumors and less than 2% amongst all lymphomas in adults. However, the definition of primary bone lymphoma has been inconsistent over time. Within our institution, we identified four cases of primary bone lymphoma based on diagnostic criteria formed from the general consensus of multiple organizations, including the World Health Organization (WHO) and International Extranodal Lymphoma Study Group (IELSG). Here, we discuss the distinct characteristics amongst these cases in addition to performing a systematic review of current literature regarding this lymphoproliferative entity. |
| format | Article |
| id | doaj-art-d3d398a8c8ff49bda709482c9b7c851b |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-d3d398a8c8ff49bda709482c9b7c851b2025-02-03T01:04:59ZengWileyCase Reports in Hematology2090-65602090-65792020-01-01202010.1155/2020/42548034254803Primary Bone Lymphoma: A Case Series and Review of LiteraturePoorva Bindal0Aakash Desai1Lukas Delasos2Sudhanshu Mulay3James Vredenburgh4Department of Hematology and Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USADepartment of Internal Medicine, University of Connecticut Health Center, Farmington, CT, USADepartment of Internal Medicine, University of Connecticut Health Center, Farmington, CT, USADepartment of Hematology and Oncology, Smilow Cancer Hospital at St. Francis, Hartford, CT, USADepartment of Hematology and Oncology, Smilow Cancer Hospital at St. Francis, Hartford, CT, USAPrimary bone lymphoma (PBL) is a subtype of lymphoma that exclusively affects skeletal tissue. Despite the relatively common involvement of skeletal structures as a manifestation of non-Hodgkin’s lymphoma (NHL), primary and exclusive involvement of the skeletal system is rare. The prevalence of PBL is estimated to be 3–7% amongst primary bone tumors and less than 2% amongst all lymphomas in adults. However, the definition of primary bone lymphoma has been inconsistent over time. Within our institution, we identified four cases of primary bone lymphoma based on diagnostic criteria formed from the general consensus of multiple organizations, including the World Health Organization (WHO) and International Extranodal Lymphoma Study Group (IELSG). Here, we discuss the distinct characteristics amongst these cases in addition to performing a systematic review of current literature regarding this lymphoproliferative entity.http://dx.doi.org/10.1155/2020/4254803 |
| spellingShingle | Poorva Bindal Aakash Desai Lukas Delasos Sudhanshu Mulay James Vredenburgh Primary Bone Lymphoma: A Case Series and Review of Literature Case Reports in Hematology |
| title | Primary Bone Lymphoma: A Case Series and Review of Literature |
| title_full | Primary Bone Lymphoma: A Case Series and Review of Literature |
| title_fullStr | Primary Bone Lymphoma: A Case Series and Review of Literature |
| title_full_unstemmed | Primary Bone Lymphoma: A Case Series and Review of Literature |
| title_short | Primary Bone Lymphoma: A Case Series and Review of Literature |
| title_sort | primary bone lymphoma a case series and review of literature |
| url | http://dx.doi.org/10.1155/2020/4254803 |
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