Efficacy and Safety of 'Fixed Dose' versus 'Loose' Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial.

Efficacy and Safety of 'Fixed Dose' versus 'Loose' Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial.

<h4>Background</h4>There are limited data on the performance of the use of fixed-dose combination (FDC) TB drugs when used under programmatic settings in high TB-endemic countries. We evaluated the efficacy and safety of FDC versus loose formulation (LF) TB treatment regimens for treatme...

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Main Authors: Abraham Aseffa, Joseph N Chukwu, Mahnaz Vahedi, Emmanuel N Aguwa, Ahmed Bedru, Tesfamariam Mebrahtu, Oliver C Ezechi, Getnet Yimer, Lawrence K Yamuah, Girmay Medhin, Cathy Connolly, Wasima Rida, Getachew Aderaye, Alimuddin I Zumla, Philip C Onyebujoh, 4FDC Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0157434&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0157434&type=printable

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