Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia
Leptospirosis is a globally significant yet often overlooked zoonotic infection. Several regions in Indonesia are endemic for leptospirosis, including East Java. Pasuruan a region located in the East Java province of Indonesia, has been recognized as an enzootic area of plague infection. However, th...
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| Format: | Article |
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Universitas Sultan Agung Semarang
2024-06-01
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| Series: | Sains Medika |
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| Online Access: | https://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/37499 |
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| author | Siti Amanah Febriani Kurnia Ritma Dhanti Kurniawan Kurniawan Ristiyanto Ristiyanto Arief Junaedi Caecilia Hapsari Ceriapuri Sukowati Farida Dwi Handayani |
| author_facet | Siti Amanah Febriani Kurnia Ritma Dhanti Kurniawan Kurniawan Ristiyanto Ristiyanto Arief Junaedi Caecilia Hapsari Ceriapuri Sukowati Farida Dwi Handayani |
| author_sort | Siti Amanah Febriani |
| collection | DOAJ |
| description | Leptospirosis is a globally significant yet often overlooked zoonotic infection. Several regions in Indonesia are endemic for leptospirosis, including East Java. Pasuruan a region located in the East Java province of Indonesia, has been recognized as an enzootic area of plague infection. However, the presence of other rodent-borne diseases has not been reported. This study aims to detect the presence of pathogenic Leptospira in rats and small mammals in the enzootic plague area of Pasuruan in Indonesia. This study belongs to the type of observational analytic research with a cross-sectional study design. Simple random sampling was conducted to trap a total of 119 forms 107 rats and 12 small mammal kidneys were analyzed molecularly (PCR) to detect Leptospira bacteria with the LipL32 gene as the target. The study revealed that 7.6% (9/119) of rats in the enzootic areas of plague (Sedaeng, Tosari, Surorowo, Petren, Pakis Bincil, Kutukan) were found to carry Leptospira DNA, indicating a significant difference between infection rates per region (p < 0.0001). Rattus tanezumi was identified as the Leptospirosis reservoir in settlements habitats with a percentage of 13.2%, Rattus tiomanicus was detected at 28.6% in forest habitats, and Rattus exulans was found at 4.4% in both habitats. The findings in our study, it is crucial for the community to increase awareness of the spread of rodent-borne diseases, including Leptospirosis. |
| format | Article |
| id | doaj-art-d3c69f7fd76a48e5a710ad63c920e5bf |
| institution | Kabale University |
| issn | 2085-1545 2339-093X |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Universitas Sultan Agung Semarang |
| record_format | Article |
| series | Sains Medika |
| spelling | doaj-art-d3c69f7fd76a48e5a710ad63c920e5bf2025-02-03T08:04:20ZengUniversitas Sultan Agung SemarangSains Medika2085-15452339-093X2024-06-0115171410.30659/sainsmed.v15i1.374999761Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan IndonesiaSiti Amanah Febriani0Kurnia Ritma Dhanti1Kurniawan Kurniawan2Ristiyanto Ristiyanto3Arief Junaedi4Caecilia Hapsari Ceriapuri Sukowati5Farida Dwi Handayani6Medical Laboratory Technology Study Program, Faculty Health Science, Universitas Muhammadiyah PurwokertoMedical Laboratory Technology Study Program, Faculty Health Science, Universitas Muhammadiyah PurwokertoMedical Laboratory Technology Study Program, Faculty Health Science, Universitas Muhammadiyah PurwokertoResearch Center for Public Health and Nutrition, National Research and Innovation Agency of Indonesia (BRIN)Pasuruan Health Office, East Java,Eijkman Research Center for Molecular Biology, National Research and Innovation Agency of Indonesia (BRIN)Eijkman Research Center for Molecular Biology, National Research and Innovation Agency of Indonesia (BRIN)Leptospirosis is a globally significant yet often overlooked zoonotic infection. Several regions in Indonesia are endemic for leptospirosis, including East Java. Pasuruan a region located in the East Java province of Indonesia, has been recognized as an enzootic area of plague infection. However, the presence of other rodent-borne diseases has not been reported. This study aims to detect the presence of pathogenic Leptospira in rats and small mammals in the enzootic plague area of Pasuruan in Indonesia. This study belongs to the type of observational analytic research with a cross-sectional study design. Simple random sampling was conducted to trap a total of 119 forms 107 rats and 12 small mammal kidneys were analyzed molecularly (PCR) to detect Leptospira bacteria with the LipL32 gene as the target. The study revealed that 7.6% (9/119) of rats in the enzootic areas of plague (Sedaeng, Tosari, Surorowo, Petren, Pakis Bincil, Kutukan) were found to carry Leptospira DNA, indicating a significant difference between infection rates per region (p < 0.0001). Rattus tanezumi was identified as the Leptospirosis reservoir in settlements habitats with a percentage of 13.2%, Rattus tiomanicus was detected at 28.6% in forest habitats, and Rattus exulans was found at 4.4% in both habitats. The findings in our study, it is crucial for the community to increase awareness of the spread of rodent-borne diseases, including Leptospirosis.https://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/37499leptospiralipl32pasuruanzoonosisindonesia |
| spellingShingle | Siti Amanah Febriani Kurnia Ritma Dhanti Kurniawan Kurniawan Ristiyanto Ristiyanto Arief Junaedi Caecilia Hapsari Ceriapuri Sukowati Farida Dwi Handayani Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia Sains Medika leptospira lipl32 pasuruan zoonosis indonesia |
| title | Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia |
| title_full | Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia |
| title_fullStr | Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia |
| title_full_unstemmed | Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia |
| title_short | Surveillance of pathogenic Leptospira among rodents and small mammals in enzootic areas of plague in Pasuruan Indonesia |
| title_sort | surveillance of pathogenic leptospira among rodents and small mammals in enzootic areas of plague in pasuruan indonesia |
| topic | leptospira lipl32 pasuruan zoonosis indonesia |
| url | https://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/37499 |
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