Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016
Hepatitis C virus (HCV) infection in pregnant women is of concern as it presents a health threat not only to the mother, but also to her infant. A retrospective analysis was performed to evaluate HCV testing and exposure in women who delivered infants between 2013 and 2016 at a referral hospital in...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2019/8654741 |
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| author | Leisha D. Nolen Courtney Gustin Sara Seeman Neil Murphy Sarah Truitt Sarah Schillie Michael G. Bruce Dana Bruden James Tiesinga Brian McMahon |
| author_facet | Leisha D. Nolen Courtney Gustin Sara Seeman Neil Murphy Sarah Truitt Sarah Schillie Michael G. Bruce Dana Bruden James Tiesinga Brian McMahon |
| author_sort | Leisha D. Nolen |
| collection | DOAJ |
| description | Hepatitis C virus (HCV) infection in pregnant women is of concern as it presents a health threat not only to the mother, but also to her infant. A retrospective analysis was performed to evaluate HCV testing and exposure in women who delivered infants between 2013 and 2016 at a referral hospital in Alaska. Multiple risk behaviors were evaluated, including drug dependency or abuse (drug abuse), tobacco use, alcohol dependency or abuse, and late presentation to prenatal care. Of the 2856 women who delivered between 2013 and 2016, 470 (16.5%) were tested for HCV during pregnancy and 1356 (47.5%) were tested at any time prior to delivery (including pregnancy); 62 (2.2%) were positive for HCV antibodies. Of the 162 women with a documented history of drug abuse, 95 (58.6%) were tested for HCV during pregnancy and 143 (88.3%) were tested at any time prior to delivery (including pregnancy); 30 (18.5%) were positive for HCV antibodies. Forty-nine women (34%) with a documented history of drug abuse who were not previously known to be HCV positive were not tested for HCV during their pregnancy. In conclusion, approximately 2% of pregnant women in the study population were known to have been exposed to HCV by the time of their delivery. One-third of women with documented drug abuse did not have an HCV test during pregnancy, revealing gaps in HCV testing of pregnant women. Further studies are needed to understand the full costs and benefits of risk-based screening versus universal screening in this and other populations. |
| format | Article |
| id | doaj-art-d3c53e75409b4f9eb8d11c2fe9a9daf4 |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-d3c53e75409b4f9eb8d11c2fe9a9daf42025-02-03T06:06:57ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972019-01-01201910.1155/2019/86547418654741Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016Leisha D. Nolen0Courtney Gustin1Sara Seeman2Neil Murphy3Sarah Truitt4Sarah Schillie5Michael G. Bruce6Dana Bruden7James Tiesinga8Brian McMahon9Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, USAObstetrics and Gynecology, Southcentral Foundation, Anchorage, AK, USAArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, USAObstetrics and Gynecology, Southcentral Foundation, Anchorage, AK, USAObstetrics and Gynecology, Southcentral Foundation, Anchorage, AK, USADivision of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, USAArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, USAArctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, USAAlaska Native Tribal Health Consortium, Anchorage, AK, USAAlaska Native Tribal Health Consortium, Anchorage, AK, USAHepatitis C virus (HCV) infection in pregnant women is of concern as it presents a health threat not only to the mother, but also to her infant. A retrospective analysis was performed to evaluate HCV testing and exposure in women who delivered infants between 2013 and 2016 at a referral hospital in Alaska. Multiple risk behaviors were evaluated, including drug dependency or abuse (drug abuse), tobacco use, alcohol dependency or abuse, and late presentation to prenatal care. Of the 2856 women who delivered between 2013 and 2016, 470 (16.5%) were tested for HCV during pregnancy and 1356 (47.5%) were tested at any time prior to delivery (including pregnancy); 62 (2.2%) were positive for HCV antibodies. Of the 162 women with a documented history of drug abuse, 95 (58.6%) were tested for HCV during pregnancy and 143 (88.3%) were tested at any time prior to delivery (including pregnancy); 30 (18.5%) were positive for HCV antibodies. Forty-nine women (34%) with a documented history of drug abuse who were not previously known to be HCV positive were not tested for HCV during their pregnancy. In conclusion, approximately 2% of pregnant women in the study population were known to have been exposed to HCV by the time of their delivery. One-third of women with documented drug abuse did not have an HCV test during pregnancy, revealing gaps in HCV testing of pregnant women. Further studies are needed to understand the full costs and benefits of risk-based screening versus universal screening in this and other populations.http://dx.doi.org/10.1155/2019/8654741 |
| spellingShingle | Leisha D. Nolen Courtney Gustin Sara Seeman Neil Murphy Sarah Truitt Sarah Schillie Michael G. Bruce Dana Bruden James Tiesinga Brian McMahon Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 Canadian Journal of Gastroenterology and Hepatology |
| title | Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 |
| title_full | Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 |
| title_fullStr | Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 |
| title_full_unstemmed | Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 |
| title_short | Risk-Based Prenatal Hepatitis C Testing Practices and Results, Alaska 2013-2016 |
| title_sort | risk based prenatal hepatitis c testing practices and results alaska 2013 2016 |
| url | http://dx.doi.org/10.1155/2019/8654741 |
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