Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection

Objective: Metabolic disruption is a central feature to many neurodegenerative diseases. Despite this, many gaps exist in our understanding of how these perturbations link to the mechanisms of neural disease. In this study, we sought to understand how genetically-controlled, cell-specific loss of py...

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Bibliographic Details
Main Authors: Thomas J. Waller, Catherine A. Collins, Monica Dus
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Molecular Metabolism
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000948
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