Development and validation of a 16-gene T-cell- related prognostic model in non-small cell lung cancer

Development and validation of a 16-gene T-cell- related prognostic model in non-small cell lung cancer

BackgroundNon-small cell lung cancer (NSCLC) exhibits variable T-cell responses, influencing prognosis and outcomes.MethodsWe analyzed 1,027 NSCLC and 108 non-cancerous samples from TCGA using ssGSEA, WGCNA, and differential expression analysis to identify T-cell-related subtypes. A prognostic model...

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Bibliographic Details
Main Authors: Anbing Zhang, Huang Ting, Jun Ma, Xiuqiong Xia, Xiaoli Lao, Siqi Li, Jianping Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
non-small cell lung cancer
T lymphocyte
prognosis
tumor immune microenvironment
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1566597/full
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