Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma

Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma

Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neopla...

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Main Authors: Viktor Proesmans, Tom Vandaele, Jan Van Slambrouck, Albert Wolthuis, André D´Hoore, Jeroen Dekervel, Eric Van Cutsem, Raphaëla Dresen, Gert De Hertogh, Karlien Degezelle, Dirk Van Raemdonck, Philippe Nafteux, Laurens J. Ceulemans
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:International Journal of Hyperthermia
Subjects:
HITHOC
pleural decortication
pseudomyxoma peritonei
Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2022.2104938
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Summary:Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery.Conclusion: ePD in combination with HITHOC is a valuable treatment for thoracic PMP.
ISSN:0265-6736
1464-5157

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