The impact of maternal systemic diseases on the occurrence of cleft lip and palate in newborns: a narrative review

The impact of maternal systemic diseases on the occurrence of cleft lip and palate in newborns: a narrative review

Cleft lip and palate (CLP) is a prevalent congenital anomaly of the maxillofacial region, characterized by abnormal openings in the lip or palate. This condition, affecting approximately 1 in 700 newborns globally, can manifest as cleft lip only, cleft palate only, or both. The etiology of CLP remai...

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Bibliographic Details
Main Authors: Hao Sui, Meijun Du, Jiali Chen, Renjie Yang, Bing Shi, Hanyao Huang, Yan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Public Health
Subjects:
CLP
maternal
pregnancy
systemic diseases
risk factors
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1568140/full
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