Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics
The past century's description of oncolytic virotherapy as a cancer treatment involving specially-engineered viruses that exploit immune deficiencies to selectively lyse cancer cells is no longer adequate. Some of the most promising therapeutic candidates are now being engineered to produce im...
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Main Authors: | Peter S. Kim, Joseph J. Crivelli, Il-Kyu Choi, Chae-Ok Yun, Joanna R. Wares |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-03-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.841 |
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