Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification
Background and Aim. We evaluated the usefulness of background coloration (BC), a color change in the area between intrapapillary capillary loops (IPCLs) in the early esophago-pharyngeal lesions using NBI with magnificaiton. Methods. Between April 2004 and March 2010, a total of 294 esophago-pharynge...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/529782 |
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| author | Hitomi Minami Haruhiro Inoue Haruo Ikeda Hitoshi Satodate Shigeharu Hamatani Kazuhiko Nakao Shin-ei Kudo |
| author_facet | Hitomi Minami Haruhiro Inoue Haruo Ikeda Hitoshi Satodate Shigeharu Hamatani Kazuhiko Nakao Shin-ei Kudo |
| author_sort | Hitomi Minami |
| collection | DOAJ |
| description | Background and Aim. We evaluated the usefulness of background coloration (BC), a color change in the area between intrapapillary capillary loops (IPCLs) in the early esophago-pharyngeal lesions using NBI with magnificaiton. Methods. Between April 2004 and March 2010, a total of 294 esophago-pharyngeal lesions were examined using NBI with magnification, and the presence of BC and IPCL patterns were assessed. Using BC, discrimination of squamous cell carcinoma (SCC) or high-grade neoplasia (HGN) from low-grade neoplasia (LGN) or nonatypia was conducted. Results. Among 294 lesions, 209 lesions (71.1%) were positive for BC, while 85 (28.9%) were negative. In the BC-positive group, 187 lesions (89.5%) were diagnosed as SCC/HGN. And 68 lesions (80.0%) in the BC-negative group were diagnosed as LGN/nonatypia. Overall accuracy of BC to discriminate SCC/HGN from LGN/nonatypia was 87.3%. The sensitivity and specificity were 91.9%, 76.7%. BC could discriminate SCC/HGN from LGN/nonatypia accurately (P<0.0001). Among 68 lesions classified into the IPCL type IV, the BC-positive group (n=26) included 21 SCC/HGN lesions, while there were 36 LGN/nonatypia lesions in the 42 BC-negative lesions. Conclusions. BC is a useful finding in differentiating SCC/HGN from LGN/nonatypia lesions in the esophagus especially when it is combined with IPCL pattern classification. |
| format | Article |
| id | doaj-art-d3427bdfeaa446219b2e6484d2a8f246 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-d3427bdfeaa446219b2e6484d2a8f2462025-02-03T01:31:58ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/529782529782Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI MagnificationHitomi Minami0Haruhiro Inoue1Haruo Ikeda2Hitoshi Satodate3Shigeharu Hamatani4Kazuhiko Nakao5Shin-ei Kudo6Digestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanDigestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanDigestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanDigestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanDigestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanDepartment of Gastroenterology and Hepatology, Nagasaki University, 1-7-1, Sakamoto, Nagasaki, JapanDigestive Disease Center, Showa University Northern Yokohama Hospital, 35-1, Chigasaki-Chuo, Tsuzuki, Yokohama 224-8503, JapanBackground and Aim. We evaluated the usefulness of background coloration (BC), a color change in the area between intrapapillary capillary loops (IPCLs) in the early esophago-pharyngeal lesions using NBI with magnificaiton. Methods. Between April 2004 and March 2010, a total of 294 esophago-pharyngeal lesions were examined using NBI with magnification, and the presence of BC and IPCL patterns were assessed. Using BC, discrimination of squamous cell carcinoma (SCC) or high-grade neoplasia (HGN) from low-grade neoplasia (LGN) or nonatypia was conducted. Results. Among 294 lesions, 209 lesions (71.1%) were positive for BC, while 85 (28.9%) were negative. In the BC-positive group, 187 lesions (89.5%) were diagnosed as SCC/HGN. And 68 lesions (80.0%) in the BC-negative group were diagnosed as LGN/nonatypia. Overall accuracy of BC to discriminate SCC/HGN from LGN/nonatypia was 87.3%. The sensitivity and specificity were 91.9%, 76.7%. BC could discriminate SCC/HGN from LGN/nonatypia accurately (P<0.0001). Among 68 lesions classified into the IPCL type IV, the BC-positive group (n=26) included 21 SCC/HGN lesions, while there were 36 LGN/nonatypia lesions in the 42 BC-negative lesions. Conclusions. BC is a useful finding in differentiating SCC/HGN from LGN/nonatypia lesions in the esophagus especially when it is combined with IPCL pattern classification.http://dx.doi.org/10.1155/2012/529782 |
| spellingShingle | Hitomi Minami Haruhiro Inoue Haruo Ikeda Hitoshi Satodate Shigeharu Hamatani Kazuhiko Nakao Shin-ei Kudo Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification Gastroenterology Research and Practice |
| title | Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification |
| title_full | Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification |
| title_fullStr | Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification |
| title_full_unstemmed | Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification |
| title_short | Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification |
| title_sort | usefulness of background coloration in detection of esophago pharyngeal lesions using nbi magnification |
| url | http://dx.doi.org/10.1155/2012/529782 |
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