Treatment of Candiduria with Micafungin: A Case Series

There has been a gradual increase in the incidence of non-Candida albicans-related nosocomial infections. Candida glabrata urinary tract infections have increased in frequency, and treating these infections can be difficult because the organism may be resistant to fluconazole. A newer antifungal age...

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Main Authors: Danny Lagrotteria, Coleman Rotstein, Christine H Lee
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2007/768734
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author Danny Lagrotteria
Coleman Rotstein
Christine H Lee
author_facet Danny Lagrotteria
Coleman Rotstein
Christine H Lee
author_sort Danny Lagrotteria
collection DOAJ
description There has been a gradual increase in the incidence of non-Candida albicans-related nosocomial infections. Candida glabrata urinary tract infections have increased in frequency, and treating these infections can be difficult because the organism may be resistant to fluconazole. A newer antifungal agent, micafungin, which belongs in the class of echinocandins, provides an alternative and effective therapy against C glabrata. The present report describes three cases of C glabrata-associated urinary tract infections successfully treated with micafungin. To the authors’ knowledge, this is the first report of successful treatment of C glabrata and azole-resistant C albicans-associated urinary tract infection with an echinocandin.
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-d315a73b783d40fbb7a5710c16a8048c2025-08-20T03:24:12ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322007-01-0118214915010.1155/2007/768734Treatment of Candiduria with Micafungin: A Case SeriesDanny Lagrotteria0Coleman Rotstein1Christine H Lee2Department of Medicine, McMaster University, CanadaDepartment of Medicine, McMaster University, CanadaDepartment of Medicine, McMaster University, CanadaThere has been a gradual increase in the incidence of non-Candida albicans-related nosocomial infections. Candida glabrata urinary tract infections have increased in frequency, and treating these infections can be difficult because the organism may be resistant to fluconazole. A newer antifungal agent, micafungin, which belongs in the class of echinocandins, provides an alternative and effective therapy against C glabrata. The present report describes three cases of C glabrata-associated urinary tract infections successfully treated with micafungin. To the authors’ knowledge, this is the first report of successful treatment of C glabrata and azole-resistant C albicans-associated urinary tract infection with an echinocandin.http://dx.doi.org/10.1155/2007/768734
spellingShingle Danny Lagrotteria
Coleman Rotstein
Christine H Lee
Treatment of Candiduria with Micafungin: A Case Series
Canadian Journal of Infectious Diseases and Medical Microbiology
title Treatment of Candiduria with Micafungin: A Case Series
title_full Treatment of Candiduria with Micafungin: A Case Series
title_fullStr Treatment of Candiduria with Micafungin: A Case Series
title_full_unstemmed Treatment of Candiduria with Micafungin: A Case Series
title_short Treatment of Candiduria with Micafungin: A Case Series
title_sort treatment of candiduria with micafungin a case series
url http://dx.doi.org/10.1155/2007/768734
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