Endothelial cell activation enhances thromboinflammation in vaccine-induced immune thrombotic thrombocytopenia

Endothelial cell activation enhances thromboinflammation in vaccine-induced immune thrombotic thrombocytopenia

Abstract: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but serious complication of the ChAdOx1 nCOV-19 vaccine. In Australia, the diagnosis of VITT required the detection of antibodies against platelet factor 4 (PF4) in plasma using a PF4/polyanion enzyme-linked immunosorbent...

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Bibliographic Details
Main Authors: Alexander Dupuy, Xiaoming Liu, Yvonne Kong, Miao Qi, Jose Perdomo, Jemma Fenwick, Jessica Tieng, Bede Johnston, Qiyu Sara Shi, Mark Larance, Yingqi Zhang, Lining Arnold Ju, Paul Coleman, Jennifer Gamble, Elizabeth E. Gardiner, Mortimer Poncz, Huyen Tran, Vivien Chen, Freda H. Passam
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925001648
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