Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)

A 65-year-old female presented with visual disturbance in her right eye lasting for over 2 months. Following investigations, she was diagnosed with MacTel type 1 in the right eye. Visual symptoms were refractory to initial treatment with intravitreal bevacizumab and thereafter intravtireal triamicin...

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Main Authors: Mohamed Loutfi, Thomas Papathomas, Ahmed Kamal
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2014/231913
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author Mohamed Loutfi
Thomas Papathomas
Ahmed Kamal
author_facet Mohamed Loutfi
Thomas Papathomas
Ahmed Kamal
author_sort Mohamed Loutfi
collection DOAJ
description A 65-year-old female presented with visual disturbance in her right eye lasting for over 2 months. Following investigations, she was diagnosed with MacTel type 1 in the right eye. Visual symptoms were refractory to initial treatment with intravitreal bevacizumab and thereafter intravtireal triamicinolone. The patient was then treated with Ozurdex, following which central macular thickness (CMT) decreased (from 397 μm to 286 μm) and visual acuity deteriorated (from logMAR 0.48 to 0.59). At 14 weeks posttreatment with Ozurdex, a recurrence of cystoid macular oedema (CMO) was observed. Following a second Ozurdex, visual acuity improved (from logMAR 0.7 to 0.64) and CMT decreased (from 349 μm to 279 μm). An additional recurrence of CMO was observed at eighteen weeks following the second Ozurdex. Following a third Ozurdex injection visual acuity deteriorated (from logMAR 0.74 to 0.78) and CMT decreased (from 332 μm to 279 μm). Conclusion. Treatment of macular oedema secondary to MacTel with Ozurdex demonstrated promising anatomical outcomes. However, visual outcomes continued to gradually deteriorate.
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spelling doaj-art-d2eeaacc053747249eabe285f5e7852e2025-02-03T05:46:45ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302014-01-01201410.1155/2014/231913231913Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)Mohamed Loutfi0Thomas Papathomas1Ahmed Kamal2University of Liverpool Medical School, Liverpool L69 3BX, UKEye Unit, Royal Cornwall Hospital, Treliske, Truro TR1 3LJ, UKOphthalmology Department, Aintree University Hospital, Longmoor Lane, Liverpool L9 7AL, UKA 65-year-old female presented with visual disturbance in her right eye lasting for over 2 months. Following investigations, she was diagnosed with MacTel type 1 in the right eye. Visual symptoms were refractory to initial treatment with intravitreal bevacizumab and thereafter intravtireal triamicinolone. The patient was then treated with Ozurdex, following which central macular thickness (CMT) decreased (from 397 μm to 286 μm) and visual acuity deteriorated (from logMAR 0.48 to 0.59). At 14 weeks posttreatment with Ozurdex, a recurrence of cystoid macular oedema (CMO) was observed. Following a second Ozurdex, visual acuity improved (from logMAR 0.7 to 0.64) and CMT decreased (from 349 μm to 279 μm). An additional recurrence of CMO was observed at eighteen weeks following the second Ozurdex. Following a third Ozurdex injection visual acuity deteriorated (from logMAR 0.74 to 0.78) and CMT decreased (from 332 μm to 279 μm). Conclusion. Treatment of macular oedema secondary to MacTel with Ozurdex demonstrated promising anatomical outcomes. However, visual outcomes continued to gradually deteriorate.http://dx.doi.org/10.1155/2014/231913
spellingShingle Mohamed Loutfi
Thomas Papathomas
Ahmed Kamal
Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
Case Reports in Ophthalmological Medicine
title Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
title_full Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
title_fullStr Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
title_full_unstemmed Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
title_short Macular Oedema Related to Idiopathic Macular Telangiectasia Type 1 Treated with Dexamethasone Intravitreal Implant (Ozurdex)
title_sort macular oedema related to idiopathic macular telangiectasia type 1 treated with dexamethasone intravitreal implant ozurdex
url http://dx.doi.org/10.1155/2014/231913
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AT thomaspapathomas macularoedemarelatedtoidiopathicmaculartelangiectasiatype1treatedwithdexamethasoneintravitrealimplantozurdex
AT ahmedkamal macularoedemarelatedtoidiopathicmaculartelangiectasiatype1treatedwithdexamethasoneintravitrealimplantozurdex