RNF128 deficiency in macrophages promotes colonic inflammation by suppressing the autophagic degradation of S100A8
Abstract Macrophages play important roles in maintaining intestinal homeostasis and in the pathogenesis of inflammatory bowel diseases (IBDs). However, the underlying mechanisms that govern macrophage-mediated inflammation are still largely unknown. In this study, we report that RNF128 is downregula...
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Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-025-07338-0 |
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