Study on HIF-PHI combined with iron supplement in treatment of renal anemia in rats

Study on HIF-PHI combined with iron supplement in treatment of renal anemia in rats

Abstract Background Roxadustat is a novel hypoxia- inducible factor-prolyl hydroxylase inhibitor(HIF-PHI) used to treat anemia in chronic kidney disease (CKD) patients. It has been reported that roxadustat can slow down kidney damage and delay the development of kidney fibrosis. Anemia and iron defi...

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Bibliographic Details
Main Authors: Zhaoli Gao, Yanxia Gao, Qiang Wang, Qi Wang, Peng Lu, Hailin Lv, Haoran Xue, Xiaotian Ma, Shuen Li, Zhao Hu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Nephrology
Subjects:
Hypoxia- inducible factor-prolyl hydroxylase inhibitor
Roxadustat
Polysaccharide iron complex
Chronic kidney disease
Renal fibrosis
Online Access:https://doi.org/10.1186/s12882-025-04045-y
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https://doi.org/10.1186/s12882-025-04045-y

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