CAR T expansion and systemic inflammation: diverging impacts on large B-cell lymphoma therapy in the multicenter CART SIE study

CAR T expansion and systemic inflammation: diverging impacts on large B-cell lymphoma therapy in the multicenter CART SIE study

CAR T expansion has been linked to anti-tumor response in relapsed/refractory large B-cell lymphoma both in clinical trials and smaller real-world studies. Here, we present the largest multicenter real-world analysis to date, evaluating 262 patients treated with tisagenlecleucel or axicabtagene cil...

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Main Authors: Martina Magni, Sadhana Jonnalagadda, Francesca Bonifazi, Massimiliano Bonafe, Silva Ljevar, Giada Zanirato, Serena De Matteis, Federico Stella, Angelica Barone, Giulia Bertolini, Anisa Bermema, Annalisa Chiappella, Maria Chiara Tisi, Ilaria Cutini, Mattia Novo, Giovanni Grillo, Mirko Farina, Massimo Martino, Mauro Krampera, Massimo Massaia, Luca Arcaini, Stefania Bramanti, Pier Luigi Zinzani, Anna Dodero, Paolo Corradini, Cristiana Carniti
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-05-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12086
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