Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain
Gut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter....
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2021/6699268 |
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| author | Hao-Ming Xu Hong-Li Huang You-Lian Zhou Hai-Lan Zhao Jing Xu Di-Wen Shou Yan-Di Liu Yong-Jian Zhou Yu-Qiang Nie |
| author_facet | Hao-Ming Xu Hong-Li Huang You-Lian Zhou Hai-Lan Zhao Jing Xu Di-Wen Shou Yan-Di Liu Yong-Jian Zhou Yu-Qiang Nie |
| author_sort | Hao-Ming Xu |
| collection | DOAJ |
| description | Gut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter. It has been proved to be an effective treatment for recurrent Clostridium difficile infection. Studies show that the gut microbiota plays an important role in the pathophysiology of neurological and psychiatric disorders through the microbiota-gut-brain axis. Therefore, reconstruction of the healthy gut microbiota is a promising new strategy for treating cerebral diseases. We have reviewed the latest research on the role of gut microbiota in different nervous system diseases as well as FMT in the context of its application in neurological, psychiatric, and other nervous system-related diseases (Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, epilepsy, autism spectrum disorder, bipolar disorder, hepatic encephalopathy, neuropathic pain, etc.). |
| format | Article |
| id | doaj-art-d2c6840abea74d93967e3ecb49ba9a45 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-d2c6840abea74d93967e3ecb49ba9a452025-02-03T01:25:26ZengWileyGastroenterology Research and Practice1687-61211687-630X2021-01-01202110.1155/2021/66992686699268Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the BrainHao-Ming Xu0Hong-Li Huang1You-Lian Zhou2Hai-Lan Zhao3Jing Xu4Di-Wen Shou5Yan-Di Liu6Yong-Jian Zhou7Yu-Qiang Nie8Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaDepartment of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, ChinaGut dysbacteriosis is closely related to various intestinal and extraintestinal diseases. Fecal microbiota transplantation (FMT) is a biological therapy that entails transferring the gut microbiota from healthy individuals to patients in order to reconstruct the intestinal microflora in the latter. It has been proved to be an effective treatment for recurrent Clostridium difficile infection. Studies show that the gut microbiota plays an important role in the pathophysiology of neurological and psychiatric disorders through the microbiota-gut-brain axis. Therefore, reconstruction of the healthy gut microbiota is a promising new strategy for treating cerebral diseases. We have reviewed the latest research on the role of gut microbiota in different nervous system diseases as well as FMT in the context of its application in neurological, psychiatric, and other nervous system-related diseases (Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, epilepsy, autism spectrum disorder, bipolar disorder, hepatic encephalopathy, neuropathic pain, etc.).http://dx.doi.org/10.1155/2021/6699268 |
| spellingShingle | Hao-Ming Xu Hong-Li Huang You-Lian Zhou Hai-Lan Zhao Jing Xu Di-Wen Shou Yan-Di Liu Yong-Jian Zhou Yu-Qiang Nie Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain Gastroenterology Research and Practice |
| title | Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain |
| title_full | Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain |
| title_fullStr | Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain |
| title_full_unstemmed | Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain |
| title_short | Fecal Microbiota Transplantation: A New Therapeutic Attempt from the Gut to the Brain |
| title_sort | fecal microbiota transplantation a new therapeutic attempt from the gut to the brain |
| url | http://dx.doi.org/10.1155/2021/6699268 |
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