Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori
Abstract Objective: To determine the role of upper GI endoscopy and gastric biopsy to rule out H. Pylori (in patients with long-standing stomach symptoms), which is a manageable cause of chronic dyspepsia. Methods: This cross-sectional study was conducted at the medical OPDSheikh Zayed Hospital...
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Rawalpindi Medical University
2024-06-01
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| Series: | Journal of Rawalpindi Medical College |
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| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/2496 |
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| author | Muhammad Zafar Majeed Ghulam Mustafa Haseeb Ahsan |
| author_facet | Muhammad Zafar Majeed Ghulam Mustafa Haseeb Ahsan |
| author_sort | Muhammad Zafar Majeed |
| collection | DOAJ |
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Abstract
Objective: To determine the role of upper GI endoscopy and gastric biopsy to rule out H. Pylori (in patients with long-standing stomach symptoms), which is a manageable cause of chronic dyspepsia.
Methods: This cross-sectional study was conducted at the medical OPDSheikh Zayed Hospital, Rahim Yar Khan. The sample size was 125 patients, having symptoms of chronic dyspepsia. Endoscopy of the participants has been done after getting informed consent. After histopathological analysis, the results were analyzed by SPSS version 23.0. The presence of H pylori has been evaluated in participants of different age groups, residences, symptoms, and conditions.
Results: According to the analysed results, a total of 85 (68%) participants have been diagnosed with the presence of H. Pylori. Prevalence of H. Pylori is highest in the age group of 50 and above i.e. 28 (73.7%), followed by the age group 30-49 43 (67.2%), (p=0.5). There is a slightly higher ratio of H. Pylori in males i.e. 47 (72.3%) than in females i.e. 38 (63.3 Chronic dyspepsia patients who had a gastric ulcer on endoscopy had a dominant proportion of 20 (83.3%) who had H. pylori too on biopsy (p=0.07), similarly, patients who had duodenal ulcers also showed a dominant proportion 29 (80.5%) of a positive result for H. pylori on biopsy (p=0.05).
Conclusion: The presence of H pylori was more than in patients above 30 years of age. So, it is better to have an endoscopic investigation to rule out any malignancy. Endoscopy is more beneficial and easily available in most parts of the country.
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| format | Article |
| id | doaj-art-d2c557cc642d4272bdf40ba6f45c329d |
| institution | Kabale University |
| issn | 1683-3562 1683-3570 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Rawalpindi Medical University |
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| series | Journal of Rawalpindi Medical College |
| spelling | doaj-art-d2c557cc642d4272bdf40ba6f45c329d2025-02-06T08:37:11ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702024-06-0128210.37939/jrmc.v28i2.2496Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. PyloriMuhammad Zafar Majeed0Ghulam Mustafa1Haseeb Ahsan2Department of Medicine. Sheikh Zayed Medical College. Rahim Yar KhanDepartment of Community Medicine, Sheikh Zayed Medical College. Rahim Yar Khan3. PGR, College of physicians and Surgeons, Pakistan, Sheikh Zayed Hospital, Rahim Yar Khan Abstract Objective: To determine the role of upper GI endoscopy and gastric biopsy to rule out H. Pylori (in patients with long-standing stomach symptoms), which is a manageable cause of chronic dyspepsia. Methods: This cross-sectional study was conducted at the medical OPDSheikh Zayed Hospital, Rahim Yar Khan. The sample size was 125 patients, having symptoms of chronic dyspepsia. Endoscopy of the participants has been done after getting informed consent. After histopathological analysis, the results were analyzed by SPSS version 23.0. The presence of H pylori has been evaluated in participants of different age groups, residences, symptoms, and conditions. Results: According to the analysed results, a total of 85 (68%) participants have been diagnosed with the presence of H. Pylori. Prevalence of H. Pylori is highest in the age group of 50 and above i.e. 28 (73.7%), followed by the age group 30-49 43 (67.2%), (p=0.5). There is a slightly higher ratio of H. Pylori in males i.e. 47 (72.3%) than in females i.e. 38 (63.3 Chronic dyspepsia patients who had a gastric ulcer on endoscopy had a dominant proportion of 20 (83.3%) who had H. pylori too on biopsy (p=0.07), similarly, patients who had duodenal ulcers also showed a dominant proportion 29 (80.5%) of a positive result for H. pylori on biopsy (p=0.05). Conclusion: The presence of H pylori was more than in patients above 30 years of age. So, it is better to have an endoscopic investigation to rule out any malignancy. Endoscopy is more beneficial and easily available in most parts of the country. https://www.journalrmc.com/index.php/JRMC/article/view/2496EndoscopyBiopsyChronic dyspepsiaHelicobacter pylori |
| spellingShingle | Muhammad Zafar Majeed Ghulam Mustafa Haseeb Ahsan Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori Journal of Rawalpindi Medical College Endoscopy Biopsy Chronic dyspepsia Helicobacter pylori |
| title | Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori |
| title_full | Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori |
| title_fullStr | Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori |
| title_full_unstemmed | Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori |
| title_short | Role Of Endoscopic Gastric Biopsy in Patients With Chronic Dyspepsia For Diagnosis Of H. Pylori |
| title_sort | role of endoscopic gastric biopsy in patients with chronic dyspepsia for diagnosis of h pylori |
| topic | Endoscopy Biopsy Chronic dyspepsia Helicobacter pylori |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/2496 |
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