Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital
Backgrounds: Malaria is a major public health problem in the tropical and subtropical areas of the world, including Africa. Most cases of malaria in Africa are caused by Plasmodium falciparum. Objectives: This study was aimed to assess the hematological changes in patient with falciparum malaria and...
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| Format: | Article |
| Language: | English |
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Knowledge E
2019-03-01
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| Series: | Sudan Journal of Medical Sciences |
| Online Access: | https://knepublishing.com/index.php/SJMS/article/view/4378 |
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| author | Abdelnassir M. Ahamed Hafiz Ahmed Hobiel Gad Allah Modawe Mohammed Saeed Elsammani |
| author_facet | Abdelnassir M. Ahamed Hafiz Ahmed Hobiel Gad Allah Modawe Mohammed Saeed Elsammani |
| author_sort | Abdelnassir M. Ahamed |
| collection | DOAJ |
| description | Backgrounds: Malaria is a major public health problem in the tropical and subtropical areas of the world, including Africa. Most cases of malaria in Africa are caused by Plasmodium falciparum. Objectives: This study was aimed to assess the hematological changes in patient with falciparum malaria and to estimate the incidence of leucopenia, thrombocytopenia, and its response to anti-malaria therapy, and to correlate the association of the hematological changes with P. falciparum-positive (study group) and P. falciparumnegative (control group).
Methodology: A total of 453 participants (353 cases and 100 as control group) were enrolled in this study, all of them were randomly selected from Elnihoud Teaching Hospital, Elnihoud Locality, West Kordufan State, Sudan. Questionnaire was filled by every participant and thick and thin blood films for malaria were prepared and stained by giemsa stain and the CBC was done by sysmex automated hematological analyzer.
Results: Thrombocytopenia, leucopenia, microcytic hypochromic red blood cells and relative lymphocytosis have significant association with falciparum malaria with Pvalues 0.008, 0.001, 0.008, and 0.004, respectively.
Conclusion: Patients with thrombocytopenia and/or leucopenia with malaria should receive anti-malaria therapy and follow-up by CBC, and shouldn’t be hurried for a bone marrow examination. |
| format | Article |
| id | doaj-art-d2b98907ca074d05bc76cfa8dfb03644 |
| institution | Kabale University |
| issn | 1858-5051 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Sudan Journal of Medical Sciences |
| spelling | doaj-art-d2b98907ca074d05bc76cfa8dfb036442025-01-22T06:41:55ZengKnowledge ESudan Journal of Medical Sciences1858-50512019-03-01141243010.18502/sjms.v14i1.43784378Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching HospitalAbdelnassir M. AhamedHafiz Ahmed HobielGad Allah ModaweMohammed Saeed ElsammaniBackgrounds: Malaria is a major public health problem in the tropical and subtropical areas of the world, including Africa. Most cases of malaria in Africa are caused by Plasmodium falciparum. Objectives: This study was aimed to assess the hematological changes in patient with falciparum malaria and to estimate the incidence of leucopenia, thrombocytopenia, and its response to anti-malaria therapy, and to correlate the association of the hematological changes with P. falciparum-positive (study group) and P. falciparumnegative (control group). Methodology: A total of 453 participants (353 cases and 100 as control group) were enrolled in this study, all of them were randomly selected from Elnihoud Teaching Hospital, Elnihoud Locality, West Kordufan State, Sudan. Questionnaire was filled by every participant and thick and thin blood films for malaria were prepared and stained by giemsa stain and the CBC was done by sysmex automated hematological analyzer. Results: Thrombocytopenia, leucopenia, microcytic hypochromic red blood cells and relative lymphocytosis have significant association with falciparum malaria with Pvalues 0.008, 0.001, 0.008, and 0.004, respectively. Conclusion: Patients with thrombocytopenia and/or leucopenia with malaria should receive anti-malaria therapy and follow-up by CBC, and shouldn’t be hurried for a bone marrow examination.https://knepublishing.com/index.php/SJMS/article/view/4378 |
| spellingShingle | Abdelnassir M. Ahamed Hafiz Ahmed Hobiel Gad Allah Modawe Mohammed Saeed Elsammani Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital Sudan Journal of Medical Sciences |
| title | Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital |
| title_full | Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital |
| title_fullStr | Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital |
| title_full_unstemmed | Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital |
| title_short | Hematological Changes in Sudanese Patients with Falciparum Malaria Attending Elnihoud Teaching Hospital |
| title_sort | hematological changes in sudanese patients with falciparum malaria attending elnihoud teaching hospital |
| url | https://knepublishing.com/index.php/SJMS/article/view/4378 |
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