Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain

Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from...

Full description

Saved in:
Bibliographic Details
Main Authors: Yinxia Wang, Ligang Xing
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2020/7565962
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832547042598060032
author Yinxia Wang
Ligang Xing
author_facet Yinxia Wang
Ligang Xing
author_sort Yinxia Wang
collection DOAJ
description Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be combined with analgesic drugs in clinical guidelines. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain. In this review, we firstly presented the necessity of analgesia during the whole course of radiotherapy. We also sketched the role of oxycodone hydrochloride in radiotherapy of bone metastases and radiotherapy-induced oral mucositis. Finally, we concluded that oxycodone hydrochloride shows good efficacy and tolerance and could be used for pain management before, during, and after radiotherapy.
format Article
id doaj-art-d2a547910dff4356b3ae8909fac2fedc
institution Kabale University
issn 1203-6765
1918-1523
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Pain Research and Management
spelling doaj-art-d2a547910dff4356b3ae8909fac2fedc2025-02-03T06:46:24ZengWileyPain Research and Management1203-67651918-15232020-01-01202010.1155/2020/75659627565962Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related PainYinxia Wang0Ligang Xing1Department of Radiation Oncology, The Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, ChinaDepartment of Radiation Oncology, The Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, ChinaRadiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be combined with analgesic drugs in clinical guidelines. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain. In this review, we firstly presented the necessity of analgesia during the whole course of radiotherapy. We also sketched the role of oxycodone hydrochloride in radiotherapy of bone metastases and radiotherapy-induced oral mucositis. Finally, we concluded that oxycodone hydrochloride shows good efficacy and tolerance and could be used for pain management before, during, and after radiotherapy.http://dx.doi.org/10.1155/2020/7565962
spellingShingle Yinxia Wang
Ligang Xing
Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
Pain Research and Management
title Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
title_full Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
title_fullStr Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
title_full_unstemmed Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
title_short Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain
title_sort role of oxycodone hydrochloride in treating radiotherapy related pain
url http://dx.doi.org/10.1155/2020/7565962
work_keys_str_mv AT yinxiawang roleofoxycodonehydrochlorideintreatingradiotherapyrelatedpain
AT ligangxing roleofoxycodonehydrochlorideintreatingradiotherapyrelatedpain