Socioeconomic status correlates with clinical outcomes in patients with acral melanoma
ObjectivesThis study aimed to investigate the impact of socioeconomic status on survival in Chinese patients with acral melanoma.MethodsWe collected clinical and socioeconomic information of 298 primary acral melanoma patients and performed Kaplan–Meier curves, log-rank tests, Cox proportional hazar...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1496082/full |
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| author | Rong Huang Jiayu Wang Kelin Zheng Mengke Zhao Zhengyun Zou Zhengyun Zou Zhengyun Zou |
| author_facet | Rong Huang Jiayu Wang Kelin Zheng Mengke Zhao Zhengyun Zou Zhengyun Zou Zhengyun Zou |
| author_sort | Rong Huang |
| collection | DOAJ |
| description | ObjectivesThis study aimed to investigate the impact of socioeconomic status on survival in Chinese patients with acral melanoma.MethodsWe collected clinical and socioeconomic information of 298 primary acral melanoma patients and performed Kaplan–Meier curves, log-rank tests, Cox proportional hazards models, and Pearson’s chi-squared tests to evaluate the relationships between clinical characteristics, socioeconomic factors, and survival outcomes.ResultsAmong the clinical characteristics, age, gender, stage, Breslow thickness, and primary tumor site significantly impacted survival in acral melanoma patients (p = 0.01, p = 0.05, p < 0.01, p < 0.01, p < 0.01, respectively). Compared to individual socioeconomic factors such as education, occupation, medical insurance, and marital status, the socioeconomic level derived from these four dimensions accurately predicted patient survival. Patients with higher socioeconomic status demonstrated significantly reduced mortality risk (HR = 0.60, 95% CI = 0.40–0.91, p = 0.02). However, socioeconomic level was not found to be an independent prognostic factor for acral melanoma patients after multivariable adjustment. Notably, a negative correlation was observed between socioeconomic level and Breslow thickness.ConclusionSocioeconomic level is associated with survival in Chinese acral melanoma patients. However, this association may be attributable to Breslow thickness rather than socioeconomic status itself. |
| format | Article |
| id | doaj-art-d29e44f95f594d2ab13b85872c3e2b12 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-d29e44f95f594d2ab13b85872c3e2b122025-02-03T06:33:44ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-02-011310.3389/fpubh.2025.14960821496082Socioeconomic status correlates with clinical outcomes in patients with acral melanomaRong Huang0Jiayu Wang1Kelin Zheng2Mengke Zhao3Zhengyun Zou4Zhengyun Zou5Zhengyun Zou6Department of the Comprehensive Cancer Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, ChinaNanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, ChinaNanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, ChinaNanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of the Comprehensive Cancer Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, ChinaNanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, ChinaNanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, ChinaObjectivesThis study aimed to investigate the impact of socioeconomic status on survival in Chinese patients with acral melanoma.MethodsWe collected clinical and socioeconomic information of 298 primary acral melanoma patients and performed Kaplan–Meier curves, log-rank tests, Cox proportional hazards models, and Pearson’s chi-squared tests to evaluate the relationships between clinical characteristics, socioeconomic factors, and survival outcomes.ResultsAmong the clinical characteristics, age, gender, stage, Breslow thickness, and primary tumor site significantly impacted survival in acral melanoma patients (p = 0.01, p = 0.05, p < 0.01, p < 0.01, p < 0.01, respectively). Compared to individual socioeconomic factors such as education, occupation, medical insurance, and marital status, the socioeconomic level derived from these four dimensions accurately predicted patient survival. Patients with higher socioeconomic status demonstrated significantly reduced mortality risk (HR = 0.60, 95% CI = 0.40–0.91, p = 0.02). However, socioeconomic level was not found to be an independent prognostic factor for acral melanoma patients after multivariable adjustment. Notably, a negative correlation was observed between socioeconomic level and Breslow thickness.ConclusionSocioeconomic level is associated with survival in Chinese acral melanoma patients. However, this association may be attributable to Breslow thickness rather than socioeconomic status itself.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1496082/fullacral melanomasocioeconomic statusBreslow thicknesssurvivalprognostic factors |
| spellingShingle | Rong Huang Jiayu Wang Kelin Zheng Mengke Zhao Zhengyun Zou Zhengyun Zou Zhengyun Zou Socioeconomic status correlates with clinical outcomes in patients with acral melanoma Frontiers in Public Health acral melanoma socioeconomic status Breslow thickness survival prognostic factors |
| title | Socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| title_full | Socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| title_fullStr | Socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| title_full_unstemmed | Socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| title_short | Socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| title_sort | socioeconomic status correlates with clinical outcomes in patients with acral melanoma |
| topic | acral melanoma socioeconomic status Breslow thickness survival prognostic factors |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1496082/full |
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