Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis

A 70-year-old female patient with a history of bioprosthetic aortic valve replacement and coronary artery bypass graft presented with bioprosthetic valve failure secondary to prosthetic valve endocarditis. The patient was deemed unsuitable for surgery by the heart team, following which she underwent...

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Main Authors: Yuhan Zhou, Bo Fu, Nan Jiang, Zhigang Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1529523/full
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author Yuhan Zhou
Bo Fu
Nan Jiang
Zhigang Guo
author_facet Yuhan Zhou
Bo Fu
Nan Jiang
Zhigang Guo
author_sort Yuhan Zhou
collection DOAJ
description A 70-year-old female patient with a history of bioprosthetic aortic valve replacement and coronary artery bypass graft presented with bioprosthetic valve failure secondary to prosthetic valve endocarditis. The patient was deemed unsuitable for surgery by the heart team, following which she underwent transcatheter aortic valve-in-valve replacement. This resulted in early death due to myocardial infarction and acute heart failure. A computed tomography revealed subclinical leaflet thrombosis. This case highlights the importance of postoperative anticoagulation therapy.
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institution Kabale University
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publisher Frontiers Media S.A.
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series Frontiers in Cardiovascular Medicine
spelling doaj-art-d274134ea00646dda2aa3b4419f6fff52025-02-06T07:10:16ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-02-011210.3389/fcvm.2025.15295231529523Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditisYuhan Zhou0Bo Fu1Nan Jiang2Zhigang Guo3Clinical School of Thoracic, Tianjin Medical University, Tianjin, ChinaDepartment of Cardiovascular Surgery, Tianjin Chest Hospital, Tianjin, ChinaDepartment of Cardiovascular Surgery, Tianjin Chest Hospital, Tianjin, ChinaDepartment of Cardiovascular Surgery, Tianjin Chest Hospital, Tianjin, ChinaA 70-year-old female patient with a history of bioprosthetic aortic valve replacement and coronary artery bypass graft presented with bioprosthetic valve failure secondary to prosthetic valve endocarditis. The patient was deemed unsuitable for surgery by the heart team, following which she underwent transcatheter aortic valve-in-valve replacement. This resulted in early death due to myocardial infarction and acute heart failure. A computed tomography revealed subclinical leaflet thrombosis. This case highlights the importance of postoperative anticoagulation therapy.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1529523/fullcase reporttranscatheter aortic valve replacementvalve-in-valveleaflet thrombosismyocardial infarction
spellingShingle Yuhan Zhou
Bo Fu
Nan Jiang
Zhigang Guo
Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
Frontiers in Cardiovascular Medicine
case report
transcatheter aortic valve replacement
valve-in-valve
leaflet thrombosis
myocardial infarction
title Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
title_full Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
title_fullStr Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
title_full_unstemmed Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
title_short Case Report: Leaflet thrombosis after transcatheter valve-in-valve aortic valve replacement in prosthetic valve endocarditis
title_sort case report leaflet thrombosis after transcatheter valve in valve aortic valve replacement in prosthetic valve endocarditis
topic case report
transcatheter aortic valve replacement
valve-in-valve
leaflet thrombosis
myocardial infarction
url https://www.frontiersin.org/articles/10.3389/fcvm.2025.1529523/full
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AT nanjiang casereportleafletthrombosisaftertranscathetervalveinvalveaorticvalvereplacementinprostheticvalveendocarditis
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