Causal association of cholesterol metabolism-related proteins with hepatocellular carcinoma and dysfunction-associated steatotic liver disease: a mendelian randomization study

Abstract Background Dysregulation of cholesterol metabolism has been recognized as a critical driver in the pathogenesis of hepatic disorders, particularly hepatocellular carcinoma (HCC) and metabolic dysfunction-associated steatotic liver disease (MASLD). However, the causal relationships between c...

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Bibliographic Details
Main Authors: Dianzhe Tian, Shitao Jiang, Yaoge Liu, Han Zheng, Lei Zhang, Yiyao Xu, Xin Lu
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02321-9
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