Sudden-onset transient bilateral myopia and angle closure induced by indapamide

We present a 34-year-old patient with sudden bilateral worsening of vision. The ophthalmic examination revealed myopia, anterior chamber shallowing and acute angle closure in both eyes. The patient had initiated systemic hypertension therapy with indapamide 14 days prior to the onset of symptoms. In...

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Main Authors: Katarzyna Samelska, Ewa Strzemecka, Piotr Skopiński, Anna Zaleska-Żmijewska
Format: Article
Language:English
Published: Termedia Publishing House 2024-10-01
Series:Klinika Oczna
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Online Access:https://www.termedia.pl/Sudden-onset-transient-bilateral-myopia-and-angle-closure-induced-by-indapamide,124,54953,1,1.html
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author Katarzyna Samelska
Ewa Strzemecka
Piotr Skopiński
Anna Zaleska-Żmijewska
author_facet Katarzyna Samelska
Ewa Strzemecka
Piotr Skopiński
Anna Zaleska-Żmijewska
author_sort Katarzyna Samelska
collection DOAJ
description We present a 34-year-old patient with sudden bilateral worsening of vision. The ophthalmic examination revealed myopia, anterior chamber shallowing and acute angle closure in both eyes. The patient had initiated systemic hypertension therapy with indapamide 14 days prior to the onset of symptoms. Intraocular pressure (IOP) was elevated in both eyes (28 mmHg in right eye, 32 mmHg in left eye). Images of the anterior segment of the eye were obtained with anterior segment optical coherence tomography (AS-OCT). The anterior chamber depth (ACD) and iridotrabecular contact were measured in both eyes. The symptoms resolved three days later. The ophthalmic examination showed normal IOP and AS-OCT image. Acute-onset bilateral myopia accompanied by acute angle closure may be a side-effect of the use of systemic drugs such as topiramate, sulphonamides and, in this case, indapamide. The treatment includes causative agent withdrawal and ocular anti-hypertensive topical therapy. The case report underlines the importance of knowledge of systemic drugs’ side-effects on the eye.
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id doaj-art-d24f1df5e11d4966bee827b1db6a1633
institution Kabale University
issn 0023-2157
2719-3209
language English
publishDate 2024-10-01
publisher Termedia Publishing House
record_format Article
series Klinika Oczna
spelling doaj-art-d24f1df5e11d4966bee827b1db6a16332025-01-24T13:02:26ZengTermedia Publishing HouseKlinika Oczna0023-21572719-32092024-10-01126316416810.5114/ko.2024.14377654953Sudden-onset transient bilateral myopia and angle closure induced by indapamideKatarzyna SamelskaEwa StrzemeckaPiotr SkopińskiAnna Zaleska-ŻmijewskaWe present a 34-year-old patient with sudden bilateral worsening of vision. The ophthalmic examination revealed myopia, anterior chamber shallowing and acute angle closure in both eyes. The patient had initiated systemic hypertension therapy with indapamide 14 days prior to the onset of symptoms. Intraocular pressure (IOP) was elevated in both eyes (28 mmHg in right eye, 32 mmHg in left eye). Images of the anterior segment of the eye were obtained with anterior segment optical coherence tomography (AS-OCT). The anterior chamber depth (ACD) and iridotrabecular contact were measured in both eyes. The symptoms resolved three days later. The ophthalmic examination showed normal IOP and AS-OCT image. Acute-onset bilateral myopia accompanied by acute angle closure may be a side-effect of the use of systemic drugs such as topiramate, sulphonamides and, in this case, indapamide. The treatment includes causative agent withdrawal and ocular anti-hypertensive topical therapy. The case report underlines the importance of knowledge of systemic drugs’ side-effects on the eye.https://www.termedia.pl/Sudden-onset-transient-bilateral-myopia-and-angle-closure-induced-by-indapamide,124,54953,1,1.htmlacute angle closure indapamide myopia myopic shift sulphonamides.
spellingShingle Katarzyna Samelska
Ewa Strzemecka
Piotr Skopiński
Anna Zaleska-Żmijewska
Sudden-onset transient bilateral myopia and angle closure induced by indapamide
Klinika Oczna
acute angle closure
indapamide
myopia
myopic shift
sulphonamides.
title Sudden-onset transient bilateral myopia and angle closure induced by indapamide
title_full Sudden-onset transient bilateral myopia and angle closure induced by indapamide
title_fullStr Sudden-onset transient bilateral myopia and angle closure induced by indapamide
title_full_unstemmed Sudden-onset transient bilateral myopia and angle closure induced by indapamide
title_short Sudden-onset transient bilateral myopia and angle closure induced by indapamide
title_sort sudden onset transient bilateral myopia and angle closure induced by indapamide
topic acute angle closure
indapamide
myopia
myopic shift
sulphonamides.
url https://www.termedia.pl/Sudden-onset-transient-bilateral-myopia-and-angle-closure-induced-by-indapamide,124,54953,1,1.html
work_keys_str_mv AT katarzynasamelska suddenonsettransientbilateralmyopiaandangleclosureinducedbyindapamide
AT ewastrzemecka suddenonsettransientbilateralmyopiaandangleclosureinducedbyindapamide
AT piotrskopinski suddenonsettransientbilateralmyopiaandangleclosureinducedbyindapamide
AT annazaleskazmijewska suddenonsettransientbilateralmyopiaandangleclosureinducedbyindapamide