Update on the relevance of mechanobiological mechanisms in lung cancer

Lung tumorigenesis is characterized by mechanical perturbations at the molecular level that affect cancer development, progression and drug efficacy. Tumor expansion, alterations in the matrix stiffness and aberrant mechanical inputs lead to distorted mechanobiology of cancer and stromal cells. This...

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Bibliographic Details
Main Authors: Antonios N. Gargalionis, Kostas A. Papavassiliou, Efthimia K. Basdra, Athanasios G. Papavassiliou
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Translational Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325001068
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