A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association
Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare potentially fatal disease. We present a case of cocaine-related SISMAD in a patient with abdominal pain. A 38-year-old African American male with hypertension and alcohol, cocaine, and tobacco abuse presented with abdomina...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/2514687 |
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| author | Rayan S. El-Zein Jeffrey Sobecki Roy Greenberg Michael Keleher Robert A. Palma |
| author_facet | Rayan S. El-Zein Jeffrey Sobecki Roy Greenberg Michael Keleher Robert A. Palma |
| author_sort | Rayan S. El-Zein |
| collection | DOAJ |
| description | Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare potentially fatal disease. We present a case of cocaine-related SISMAD in a patient with abdominal pain. A 38-year-old African American male with hypertension and alcohol, cocaine, and tobacco abuse presented with abdominal pain and recent cocaine use. A CT angiogram revealed SISMAD; he was treated with conservative management. Cocaine and SISMAD share similar pathophysiologic mechanisms pertaining to vascular smooth muscle cell apoptosis and increased shear stress at fixed vascular positions. Our report emphasizes the need to consider cocaine abuse in SISMAD pathophysiology, risk stratification, and treatment algorithms in future studies. |
| format | Article |
| id | doaj-art-d20913ae0c064204bca04f8685f6fdb6 |
| institution | Kabale University |
| issn | 2090-6986 2090-6994 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Vascular Medicine |
| spelling | doaj-art-d20913ae0c064204bca04f8685f6fdb62025-02-03T05:44:12ZengWileyCase Reports in Vascular Medicine2090-69862090-69942020-01-01202010.1155/2020/25146872514687A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic AssociationRayan S. El-Zein0Jeffrey Sobecki1Roy Greenberg2Michael Keleher3Robert A. Palma4Department of Internal Medicine, OhioHealth Doctors Hospital, 5100 W Broad St, Columbus, OH 43228, USADepartment of Internal Medicine, OhioHealth Doctors Hospital, 5100 W Broad St, Columbus, OH 43228, USADepartment of Internal Medicine, OhioHealth Doctors Hospital, 5100 W Broad St, Columbus, OH 43228, USADepartment of Interventional Radiology, OhioHealth Doctors Hospital, 5100 W Broad St, Columbus, OH 43228, USADepartment of Internal Medicine, OhioHealth Doctors Hospital, 5100 W Broad St, Columbus, OH 43228, USASpontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare potentially fatal disease. We present a case of cocaine-related SISMAD in a patient with abdominal pain. A 38-year-old African American male with hypertension and alcohol, cocaine, and tobacco abuse presented with abdominal pain and recent cocaine use. A CT angiogram revealed SISMAD; he was treated with conservative management. Cocaine and SISMAD share similar pathophysiologic mechanisms pertaining to vascular smooth muscle cell apoptosis and increased shear stress at fixed vascular positions. Our report emphasizes the need to consider cocaine abuse in SISMAD pathophysiology, risk stratification, and treatment algorithms in future studies.http://dx.doi.org/10.1155/2020/2514687 |
| spellingShingle | Rayan S. El-Zein Jeffrey Sobecki Roy Greenberg Michael Keleher Robert A. Palma A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association Case Reports in Vascular Medicine |
| title | A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association |
| title_full | A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association |
| title_fullStr | A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association |
| title_full_unstemmed | A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association |
| title_short | A Spontaneous Isolated Superior Mesenteric Artery Dissection Associated with Cocaine Abuse: A Pathomechanistic Association |
| title_sort | spontaneous isolated superior mesenteric artery dissection associated with cocaine abuse a pathomechanistic association |
| url | http://dx.doi.org/10.1155/2020/2514687 |
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