Enhanced extracellular production of Coprinopsis cinerea laccase Lcc9 in Aspergillus niger by gene expression cassette and bioprocess optimization

Enhanced extracellular production of Coprinopsis cinerea laccase Lcc9 in Aspergillus niger by gene expression cassette and bioprocess optimization

Abstract Background The laccase Lcc9 from Coprinopsis cinerea has optimal catalytic activity at moderate to alkaline pH conditions, making it invaluable for industrial applications. However, C. cinerea naturally secretes Lcc9 at low expression levels, which limits the industrial application of Lcc9...

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Bibliographic Details
Main Authors: Dongbang Yao, Xiaozhuang Liu, Hui Wang, Juanjuan Liu, Zemin Fang, Yazhong Xiao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Biotechnology
Subjects:
Laccase
Aspergillus niger
Signal peptide
Promoter
Integration loci
Bioprocess
Online Access:https://doi.org/10.1186/s12896-024-00924-8
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