Resistance to ceftriaxone and penicillin G among contemporary syphilis strains confirmed by natural in vitro mutagenesis
Abstract Background For many years, syphilis treatment was considered straightforward due to the universal susceptibility of Treponema pallidum subsp. pallidum (TPA) to penicillin antibiotics. Methods Penicillin-binding protein genes from a ceftriaxone treatment failure T. pallidum isolate were asse...
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| Main Authors: | Petra Pospíšilová, Juraj Bosák, Matěj Hrala, Lenka Krbková, Eliška Vrbová, David Šmajs |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | Communications Medicine |
| Online Access: | https://doi.org/10.1038/s43856-025-00948-x |
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