Effect of chronic restraint stress on body weight of male Sprague Dawley rats

Background:  Stress disturbs body weight and food intake, but the core mechanisms are not well understood.    Study design:  Experimental     Materials and Methods:  The study was conducted in  National  Institute  of  Health  (NIH),  Islamabad Sixty male Sprague Dawley rats (mean wt 25...

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Main Authors: Sadia Moazzam, Irfan Afzal Mughal, Noor Ul Ain Irfan, Ilqa Attique, Fareeha Zaheer, Asma Irfan
Format: Article
Language:English
Published: Rawalpindi Medical University 2023-04-01
Series:Journal of Rawalpindi Medical College
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Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/1848
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author Sadia Moazzam
Irfan Afzal Mughal
Noor Ul Ain Irfan
Ilqa Attique
Fareeha Zaheer
Asma Irfan
author_facet Sadia Moazzam
Irfan Afzal Mughal
Noor Ul Ain Irfan
Ilqa Attique
Fareeha Zaheer
Asma Irfan
author_sort Sadia Moazzam
collection DOAJ
description Background:  Stress disturbs body weight and food intake, but the core mechanisms are not well understood.    Study design:  Experimental     Materials and Methods:  The study was conducted in  National  Institute  of  Health  (NIH),  Islamabad Sixty male Sprague Dawley rats (mean wt 250 ± 50 grams) were used and divided into 2 groups.   Each group comprised of 30 rats.   Group I was taken as control. Group II was exposed to chronic stress.  Results:  The comparison of weight gain by the different groups disclosed that there was a significant decrease in weight gain of rats exposed to the chronic stress as compared to control group.     Conclusion:  Chronic restraint stress has a detrimental effect on body weight.  
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institution Kabale University
issn 1683-3562
1683-3570
language English
publishDate 2023-04-01
publisher Rawalpindi Medical University
record_format Article
series Journal of Rawalpindi Medical College
spelling doaj-art-d1eb3ba6e5b14b27a254204ebc2076342025-02-06T08:43:18ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702023-04-0127110.37939/jrmc.v27i1.1848Effect of chronic restraint stress on body weight of male Sprague Dawley ratsSadia MoazzamIrfan Afzal MughalNoor Ul Ain IrfanIlqa AttiqueFareeha ZaheerAsma Irfan Background:  Stress disturbs body weight and food intake, but the core mechanisms are not well understood.    Study design:  Experimental     Materials and Methods:  The study was conducted in  National  Institute  of  Health  (NIH),  Islamabad Sixty male Sprague Dawley rats (mean wt 250 ± 50 grams) were used and divided into 2 groups.   Each group comprised of 30 rats.   Group I was taken as control. Group II was exposed to chronic stress.  Results:  The comparison of weight gain by the different groups disclosed that there was a significant decrease in weight gain of rats exposed to the chronic stress as compared to control group.     Conclusion:  Chronic restraint stress has a detrimental effect on body weight.   https://www.journalrmc.com/index.php/JRMC/article/view/1848Body weight, Chronic stress, cortisol
spellingShingle Sadia Moazzam
Irfan Afzal Mughal
Noor Ul Ain Irfan
Ilqa Attique
Fareeha Zaheer
Asma Irfan
Effect of chronic restraint stress on body weight of male Sprague Dawley rats
Journal of Rawalpindi Medical College
Body weight, Chronic stress, cortisol
title Effect of chronic restraint stress on body weight of male Sprague Dawley rats
title_full Effect of chronic restraint stress on body weight of male Sprague Dawley rats
title_fullStr Effect of chronic restraint stress on body weight of male Sprague Dawley rats
title_full_unstemmed Effect of chronic restraint stress on body weight of male Sprague Dawley rats
title_short Effect of chronic restraint stress on body weight of male Sprague Dawley rats
title_sort effect of chronic restraint stress on body weight of male sprague dawley rats
topic Body weight, Chronic stress, cortisol
url https://www.journalrmc.com/index.php/JRMC/article/view/1848
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