Effect of chronic restraint stress on body weight of male Sprague Dawley rats
Background: Stress disturbs body weight and food intake, but the core mechanisms are not well understood. Study design: Experimental Materials and Methods: The study was conducted in National Institute of Health (NIH), Islamabad Sixty male Sprague Dawley rats (mean wt 25...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2023-04-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/1848 |
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| Summary: | Background:
Stress disturbs body weight and food intake, but the core mechanisms are not well understood.
Study design: Experimental
Materials and Methods:
The study was conducted in National Institute of Health (NIH), Islamabad Sixty male Sprague Dawley rats (mean wt 250 ± 50 grams) were used and divided into 2 groups.
Each group comprised of 30 rats.
Group I was taken as control. Group II was exposed to chronic stress.
Results:
The comparison of weight gain by the different groups disclosed that there was a significant decrease in weight gain of rats exposed to the chronic stress as compared to control group.
Conclusion:
Chronic restraint stress has a detrimental effect on body weight.
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| ISSN: | 1683-3562 1683-3570 |