Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions.

The envelope glycoprotein (Env) of the Human Immunodeficiency Virus Type-1 (HIV-1) is a critical determinant of viral infectivity, tropism and is the main target for humoral immunity; however, little is known about the cellular machinery that directs Env trafficking and its incorporation into nascen...

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Bibliographic Details
Main Authors: Elisabetta Groppelli, Alice C Len, Luke A Granger, Clare Jolly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004518
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