Biological computing with diffusion and excitable calcium stores

Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calci...

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Main Authors: H. G. E. Hentschel, Alan Fine, C. S. Pencea
Format: Article
Language:English
Published: AIMS Press 2004-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147
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author H. G. E. Hentschel
Alan Fine
C. S. Pencea
author_facet H. G. E. Hentschel
Alan Fine
C. S. Pencea
author_sort H. G. E. Hentschel
collection DOAJ
description Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors forbiological signals.
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institution Kabale University
issn 1551-0018
language English
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series Mathematical Biosciences and Engineering
spelling doaj-art-d1dceb6910e74f408966d50f2039019d2025-01-24T01:46:28ZengAIMS PressMathematical Biosciences and Engineering1551-00182004-02-011114715910.3934/mbe.2004.1.147Biological computing with diffusion and excitable calcium storesH. G. E. Hentschel0Alan Fine1C. S. Pencea2Department of Physics, Emory University, Maths/Science Center, 400 Dowman Drive, Atlanta, GA 30322Department of Physiology and Biophysics, Dalhousie University, Halifax NSDepartment of Physics, Emory University, Atlanta, GA 30322Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors forbiological signals.https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147biological signaling.diffusionlogic gatescomputationcalcium-induced calcium release
spellingShingle H. G. E. Hentschel
Alan Fine
C. S. Pencea
Biological computing with diffusion and excitable calcium stores
Mathematical Biosciences and Engineering
biological signaling.
diffusion
logic gates
computation
calcium-induced calcium release
title Biological computing with diffusion and excitable calcium stores
title_full Biological computing with diffusion and excitable calcium stores
title_fullStr Biological computing with diffusion and excitable calcium stores
title_full_unstemmed Biological computing with diffusion and excitable calcium stores
title_short Biological computing with diffusion and excitable calcium stores
title_sort biological computing with diffusion and excitable calcium stores
topic biological signaling.
diffusion
logic gates
computation
calcium-induced calcium release
url https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147
work_keys_str_mv AT hgehentschel biologicalcomputingwithdiffusionandexcitablecalciumstores
AT alanfine biologicalcomputingwithdiffusionandexcitablecalciumstores
AT cspencea biologicalcomputingwithdiffusionandexcitablecalciumstores