Biological computing with diffusion and excitable calcium stores
Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calci...
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Format: | Article |
Language: | English |
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AIMS Press
2004-02-01
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Series: | Mathematical Biosciences and Engineering |
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Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147 |
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author | H. G. E. Hentschel Alan Fine C. S. Pencea |
author_facet | H. G. E. Hentschel Alan Fine C. S. Pencea |
author_sort | H. G. E. Hentschel |
collection | DOAJ |
description | Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors forbiological signals. |
format | Article |
id | doaj-art-d1dceb6910e74f408966d50f2039019d |
institution | Kabale University |
issn | 1551-0018 |
language | English |
publishDate | 2004-02-01 |
publisher | AIMS Press |
record_format | Article |
series | Mathematical Biosciences and Engineering |
spelling | doaj-art-d1dceb6910e74f408966d50f2039019d2025-01-24T01:46:28ZengAIMS PressMathematical Biosciences and Engineering1551-00182004-02-011114715910.3934/mbe.2004.1.147Biological computing with diffusion and excitable calcium storesH. G. E. Hentschel0Alan Fine1C. S. Pencea2Department of Physics, Emory University, Maths/Science Center, 400 Dowman Drive, Atlanta, GA 30322Department of Physiology and Biophysics, Dalhousie University, Halifax NSDepartment of Physics, Emory University, Atlanta, GA 30322Intracellular signaling often employs excitable stores of calciumcoupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gatesfor computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors forbiological signals.https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147biological signaling.diffusionlogic gatescomputationcalcium-induced calcium release |
spellingShingle | H. G. E. Hentschel Alan Fine C. S. Pencea Biological computing with diffusion and excitable calcium stores Mathematical Biosciences and Engineering biological signaling. diffusion logic gates computation calcium-induced calcium release |
title | Biological computing with diffusion and excitable calcium stores |
title_full | Biological computing with diffusion and excitable calcium stores |
title_fullStr | Biological computing with diffusion and excitable calcium stores |
title_full_unstemmed | Biological computing with diffusion and excitable calcium stores |
title_short | Biological computing with diffusion and excitable calcium stores |
title_sort | biological computing with diffusion and excitable calcium stores |
topic | biological signaling. diffusion logic gates computation calcium-induced calcium release |
url | https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.147 |
work_keys_str_mv | AT hgehentschel biologicalcomputingwithdiffusionandexcitablecalciumstores AT alanfine biologicalcomputingwithdiffusionandexcitablecalciumstores AT cspencea biologicalcomputingwithdiffusionandexcitablecalciumstores |